Ch:5 Enzymes

Question 1

A large Km means that the enzyme has __high/low__ affinity for substrate.

Answer 1

LOW

Question 2

A small Km means that the enzyme has __high/low__ affinity for substrate.

Answer 2

HIGH

Question 3

When discussing graphs regarding enzymes, if a competitive inhibitor is present, what will happen to the Km and Vmax?

Answer 3

Competitive Inhibitors = Km increases, Vmax decreases

Question 4

When discussing graphs regarding enzymes, if a noncompetitive inhibitor is present, what will happen to the Km and Vmax?

Answer 4

Noncompetitive Inhibitor = Km stays the same but Vmax decreases

Question 5

What is the definition of isozymes?

Answer 5

Enzymes that catalyze the same reaction but differ in subunit

Question 6

What is the definition of an allosteric enzyme?

Answer 6

An enzyme that changes conformation after binding to substrate.

Doesn’t follow hyperbolic curve as seen in Michaelis-Menton curves but follows a sigmoidal curve