CH 21 & 22 Part 3 Flashcards
What is the T in T-cell?***
Thymus
HIV destroys and hides in what cell?***
Helper T-cell
What is an antigen?
Substance that binds a T-lymphocyte or antibody
Which cell has CD4?***
Helper T-cell
Which cell has CD8?***
Cytotoxic cell
B-cells are responsible for what kind of immunity?
Humoral
Once a B-cell is activated they become __ and produce ___.
- Plasma cells
2. Antibodies
HIV kills which cells?
- Cytotoxic
- Plasma cells
- Antibodies
T-lymphocytes assist in which immunities?
- Cell mediated immunity
- Humoral immunity
- Innate immunity
Only infected cells will have?
MHC
What is a naive T-cell?
A cell that has never been to an immune responce
Where are lymphocytes formed?
Red bone marrow
What is clonal selection?***
Forming clones in response to an antigen
Swollen lymph nodes is a result of?
Clonal selection
During clonal selection what two branch cells are made?
- Effector T-cells
2. Memory cells
Which cells have IL-2 receptors?
- Helper T-cell
2. Cytotoxic
Cytotoxic cells receive external IL-2 from?
Helper T-cells
Cytotoxic cell killing phases.***
- Pathogen engulfed and presented to T-cell.
- Cytotoxic T-cell with specific TCR recognizes antigen.
- IL-2 released from helper T-cell.
- Clonal selection starts.
- Effector cytotoxic T-cells go to site of infection.
- Cytotoxic T-cells release perforin and granzymes.
Which cell has IL-4?
B-cells
Why makes effector B-cells special?
They enlarge and become plasma cells releasing antibodies.
Plasma cells function?
Release antibodies
Cytokine release helps?
- Activate B-cells
- Activate cytotoxic T-lymphocytes
- Stimulate innate system cells
How many antigens can a antibody hold?
2
What is opsonization?***
Antibody class that makes it more likely a target cell will be seen by a phagocytic cell
