CH 21 & 22 Part 3

Question 1

What is the T in T-cell?***

Answer 1

Thymus

Question 2

HIV destroys and hides in what cell?***

Answer 2

Helper T-cell

Question 3

What is an antigen?

Answer 3

Substance that binds a T-lymphocyte or antibody

Question 4

Which cell has CD4?***

Answer 4

Helper T-cell

Question 5

Which cell has CD8?***

Answer 5

Cytotoxic cell

Question 6

B-cells are responsible for what kind of immunity?

Answer 6

Humoral

Question 7

Once a B-cell is activated they become __ and produce ___.

Answer 7

1. Plasma cells

2. Antibodies

Question 8

HIV kills which cells?

Answer 8

1. Cytotoxic
2. Plasma cells
3. Antibodies

Question 9

T-lymphocytes assist in which immunities?

Answer 9

1. Cell mediated immunity
2. Humoral immunity
3. Innate immunity

Question 10

Only infected cells will have?

Answer 10

MHC

Question 11

What is a naive T-cell?

Answer 11

A cell that has never been to an immune responce

Question 12

Where are lymphocytes formed?

Answer 12

Red bone marrow

Question 13

What is clonal selection?***

Answer 13

Forming clones in response to an antigen

Question 14

Swollen lymph nodes is a result of?

Answer 14

Clonal selection

Question 15

During clonal selection what two branch cells are made?

Answer 15

1. Effector T-cells

2. Memory cells

Question 16

Which cells have IL-2 receptors?

Answer 16

1. Helper T-cell

2. Cytotoxic

Question 17

Cytotoxic cells receive external IL-2 from?

Answer 17

Helper T-cells

Question 18

Cytotoxic cell killing phases.***

Answer 18

1. Pathogen engulfed and presented to T-cell.
2. Cytotoxic T-cell with specific TCR recognizes antigen.
3. IL-2 released from helper T-cell.
4. Clonal selection starts.
5. Effector cytotoxic T-cells go to site of infection.
6. Cytotoxic T-cells release perforin and granzymes.

Question 19

Which cell has IL-4?

Answer 19

B-cells

Question 20

Why makes effector B-cells special?

Answer 20

They enlarge and become plasma cells releasing antibodies.

Question 21

Plasma cells function?

Answer 21

Release antibodies

Question 22

Cytokine release helps?

Answer 22

1. Activate B-cells
2. Activate cytotoxic T-lymphocytes
3. Stimulate innate system cells

Question 23

How many antigens can a antibody hold?

Answer 23

2

Question 24

What is opsonization?***

Answer 24

Antibody class that makes it more likely a target cell will be seen by a phagocytic cell

Question 25

What are the five classes of immunoglobulins (Ig)?***

Answer 25

1. Ig M
2. Ig A
3. Ig D
4. Ig G
5. Ig E
   (M.A.D.G.E)

Question 26

Ig G***

Answer 26

Can cross placenta and cause hemolytic disease

Question 27

Ig M***

Answer 27

1. Found mostly in blood

2. Pentamer structure (bind 10 antigens)

Question 28

Ig A***

Answer 28

1. Found in areas exposed to environment. (mucus, saliva, tears, breastmilk?

Question 29

Ig D***

Answer 29

1. Specific B-lymphocyte receptor

2. Identifies when immature B-lymphocytes are ready for activation

Question 30

Ig E ***

Answer 30

1. Responds to allergic reaction
2. Causes release of products from mast cells and basophils
3. Attracts eosinophils
4. Causes inflammation

Question 31

During a primary response which Ig are produced?***

Answer 31

1st Ig m

2nd Ig G

Question 32

During a secondary response which Ig are produced?***

Answer 32

1st Ig G

2nd Ig M