ch 18 pt 3

Question 1

ductal obstruction during lactation that can cause inflam and cyst formation

Answer 1

galctocele

Question 2

____ changes occur normally with the fluctuations of menstruation, and are either nonproliferative or proliferative

Answer 2

fibrocystic

Question 3

____ fibrocystic changes are MC, show fibrotic stroma, dilation of ducts, and NO epi layer changes

Answer 3

nonproliferative

Question 4

___ fibrocystic changes present with epi hyperplasia, and increase the risk of breast CA 5x

Answer 4

proliferative

Question 5

chalky white mass due to inflam following trauma

Answer 5

fat necrosis

Question 6

acute mastitis is MC due to an infection of what, via ducts

Answer 6

staph aureus

Question 7

inflam d/o that is due to ductal dehydration MC around 40-60, is nonbact, and is chronic

Answer 7

mammary duct ectasia

Question 8

tumors of the breast are MC ____, from epi cells

Answer 8

carcinomas

Question 9

MC BENIGN breast tumor, MC in women 20-30 yo

Answer 9

fibroadenoma

Question 10

breast tumor that can be benign (MC) or malig (15%), has leaflike projections

Answer 10

phyllodes

Question 11

lifetime risk of developing breast cancer in women

Answer 11

1:8

Question 12

MC location for breast cancer (50%)

Answer 12

superolateral quadrant

Question 13

if breast cancer is ____, it does NOT penetrate the basement membrane. if it is _____, it will

Answer 13

in situ (noninvasive)
invasive

Question 14

non invasive type breast ca that is mc unilateral, has a good prognosis

Answer 14

DCIS (ductal carcinoma in situ)

Question 15

noninvasive type breast ca that is mc bilateral and rarely calcific and therefore harder to detect

Answer 15

LCIS (lobular cacinoma in situ)

Question 16

invasive breast cancer that makes up 70-80% of all breast CA and forms out of DCIS

Answer 16

invasive ductal carcinoma

Question 17

invasive breast cancer with cells identical to LCIS

Answer 17

invasive lobular carcinoma

Question 18

___ carcinoma is rare

Answer 18

medullary

Question 19

if detected via palpation (2-3cm), invasive breast ca has a __% mets chance, but if found via mammography it is only a __%

Answer 19

50%

15%

Question 20

mets are MC via ____ system, and the location of the cancer determines the route of mets

Answer 20

lymphatic

Question 21

lateral and central tumors MC mets via _____ while medial tumors mets via the ________

Answer 21

axillary nodes

internal mammary arteries

Question 22

invasive breast ca has a poor prognosis with an overxpression of ____ (GF amp), and a better prognosis with the presence of ____ ____

Answer 22

HER2/NEU

estrogen receptors

Question 23

gynecomastia is common normally during puberty, around __%

Answer 23

70

Question 24

male breast carcinoma is known to rapidly invade the ___, MC in elderly, and __% have mets at time of dx

Answer 24

thorax

50