ch 18 pt 3 Flashcards
ductal obstruction during lactation that can cause inflam and cyst formation
galctocele
____ changes occur normally with the fluctuations of menstruation, and are either nonproliferative or proliferative
fibrocystic
____ fibrocystic changes are MC, show fibrotic stroma, dilation of ducts, and NO epi layer changes
nonproliferative
___ fibrocystic changes present with epi hyperplasia, and increase the risk of breast CA 5x
proliferative
chalky white mass due to inflam following trauma
fat necrosis
acute mastitis is MC due to an infection of what, via ducts
staph aureus
inflam d/o that is due to ductal dehydration MC around 40-60, is nonbact, and is chronic
mammary duct ectasia
tumors of the breast are MC ____, from epi cells
carcinomas
MC BENIGN breast tumor, MC in women 20-30 yo
fibroadenoma
breast tumor that can be benign (MC) or malig (15%), has leaflike projections
phyllodes
lifetime risk of developing breast cancer in women
1:8
MC location for breast cancer (50%)
superolateral quadrant
if breast cancer is ____, it does NOT penetrate the basement membrane. if it is _____, it will
in situ (noninvasive) invasive
non invasive type breast ca that is mc unilateral, has a good prognosis
DCIS (ductal carcinoma in situ)
noninvasive type breast ca that is mc bilateral and rarely calcific and therefore harder to detect
LCIS (lobular cacinoma in situ)
invasive breast cancer that makes up 70-80% of all breast CA and forms out of DCIS
invasive ductal carcinoma
invasive breast cancer with cells identical to LCIS
invasive lobular carcinoma
___ carcinoma is rare
medullary
if detected via palpation (2-3cm), invasive breast ca has a __% mets chance, but if found via mammography it is only a __%
50%
15%
mets are MC via ____ system, and the location of the cancer determines the route of mets
lymphatic
lateral and central tumors MC mets via _____ while medial tumors mets via the ________
axillary nodes
internal mammary arteries
invasive breast ca has a poor prognosis with an overxpression of ____ (GF amp), and a better prognosis with the presence of ____ ____
HER2/NEU
estrogen receptors
gynecomastia is common normally during puberty, around __%
70
male breast carcinoma is known to rapidly invade the ___, MC in elderly, and __% have mets at time of dx
thorax
50
