ch 11 pt 6

Question 1

phagocytic stem cell (macrophages, dendritic cells) that can form a benign or malignant neoplasm
-can be unisystem (bone marrow erosion) or multisystem

Answer 1

histiocyte (histiocytic neoplasm)

Question 2

“tennis racket” organelles found with langerhans cell histiocytosis of the epidermis

Answer 2

birbeck granules

Question 3

____ langerhans cell histiocytosis occurs in kids

Answer 3

multisystem

Question 4

disseminated intravascular coagulation
immune thrombocytopenia purpura
von willebrand disease
hemophilia a and b 
-- are all \_\_\_ disorders

Answer 4

bleeding

Question 5

widspread thrombi/clots from sepsis, endothelial injury from sle/stroke, or severe tissue injury like MVA or occupational

Answer 5

disseminated intravascular coagulation

Question 6

disseminated intravascular coagulation tx is either __ or ___, as it can either cause excessive clotting or excessive bleeding

Answer 6

anti coagulants

coagulants

Question 7

general term with decreased cell number

Answer 7

thrombocytopenia

Question 8

with thrombocytopenia, increased ____ bleeding shows around 20k-50k cells, while increased ____ bleeding shows

Answer 8

post-traumatic

spontaneous

Question 9

bleeding d/o in which antibodies attack platelet membranes and cause red/purple skin discoloration

Answer 9

ITP (immune thrombocytopenic purpura)

Question 10

___ ITP is in children 2* to viral infx and is self limiting while ___ ITP is in F 20-40, insidious and from ADRs, lymphoma, or idiopathic

Answer 10

acute

chronic

Question 11

MC inherited bleeding d/o that affects 1% of US, presents with bleeding gums, easy bruising

Answer 11

von willebrand disease

Question 12

von willebrand disease occurs due to decreased or lacking _____ which causes dysfunctional platelet adherence to vessel wall

Answer 12

vWF (von willebrand factor)

Question 13

hemophilia A and B are both x linked recessive mc in males, but A is due to mutated coagulation factor ___ while less common B is due to mutated coagulation factor ___

Answer 13

VIII

IX

Question 14

hemophilia A and B tx involves ___ of their respective coagulation factors (VIII and IX respectively)

Answer 14

infusion

Question 15

___ ___ occurs in pt with myasthenia gravis, SLE, RA, and is due to reactive b cells within the THYMUS

Answer 15

thymic hyperplasia

Question 16

rare carcinoma that can be benign OR malignant mc affects adults of MG pt and presents with a cough, dyspnea, svcs if obstructive

Answer 16

thymoma