ch 18 pt 1 Flashcards

1
Q

___ of the vulva is mc and ___ is rare

A

inflammation

neoplasia

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2
Q

inflam of vulva that has many causes including allergic contact dermatitis (eczema), skin infx or a bartholin’s cyst which can obstruct a duct

A

vulvitis

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3
Q

epi thinning that causes white lesion near labia minora from an idiopathic cause, mc thought to be autoimmune

A

lichen sclerosis

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4
Q

mc demographic for lichen sclerosus, which has a small (1-5% SCC) ca risk

A

elderly

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5
Q

epi hyperplasia and hyperkeratosis from chronic irritation, shows with leukocytes and NO CA RISK

A

lichen simplex chronicus

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6
Q

though both resemble leukoplakia, lichen sclerosis has ___ epi while lichen simplex chronicus has ___ epi

  • LS has MIN dermal inflam
  • LSC has dermal inflam + leukocytes
A

thinned

thickened

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7
Q
  • condylomata ____ is a secondary syph infection with flat, moist, painless warty lesions
  • condylomata ____ is genital warts (HPV6,11)
A

lata

acuminata

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8
Q

vulvar carcinoma is rare, mc in those >60 yo, but ___% is SCC

A

90

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9
Q

HPV-related SCC follows vulvar ___ ___ (VIN), a pre-ca lesion or HPV __ and ___ (both high risk)

A

intraepithelial neoplasia

16 and 18

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10
Q

non HPV related SCC is MC and is seen in older women, and follows ___ ____, no VIN

A

lichen sclerosis

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11
Q

common, benign and transient inflam of vagina that may present with leukorrhea, pain, pruritis
-bact or fungi infx

A

vaginitis

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12
Q

vaginal SCC is rare but is mc in those > __ yo, and in pt with ___

A

60

HPV

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13
Q

type of rare vaginal CA with red/granular foci that is a result from an ADR in mothers who took DIETHYLSTILBESTROL (DES)

A

clear cell adenocarcinoma

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14
Q

type of embryonal rhabdomyosarcoma mc seen in pt less that 5 yo

A

sarcoma botryoides

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15
Q

___ is common and benign and possibly asymptomatic though may present with leukorrhea, pain, bleeding - and should prompt pelvic exam

A

cervicitis

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16
Q

MC cause of infectious cervitis

A

chlamydia trachomatis

17
Q

high risk HPV (2), that have a 70% of evolving into ca, esp in the TRANSFORMATION ZONE

A

16

18

18
Q

most HPV inx are ___ for months, only a few persist into cervical intraepi neoplasia (CIN)

A

transient

19
Q

the _____ zone is within the cervix and everts during puberty when columnar cells undergo squamous metaplasia

A

transformation

20
Q

neoplasia of cervix from HPV to dysplasia (pre-ca lesion) that is MC dx at 30 yo
-is usually asymptomatic

A

CIN

21
Q
  • ____ (CIN I) req only observation as 60% regress and 10% progress to next stage
  • ____ (CIN II-III) req excision as only 30% regress and 10% prog into CA
A

low grade

high grade

22
Q
  • progressive change from normal to cancerous cells in CIN

- enlarged nucleus, anaplasia, irreg borders, dark

A

koilocytosis

23
Q

biopsy for CIN following an abnormal pap smear

A

colposcopy

24
Q

invasive carcinoma of the cervix (ICC) is ___% mc SCC, and is MC dx in mid ___

A

75%

40s

25
Q

with a cervical lesion less than 3mm, the chance of mets is __%, but with a lesion greater than 3mm the chance is __%

A

1

10

26
Q

early on ICC is asymptomatic but can cause local invasion and is commonly lethal due to obstruction and renal failure, which is why this population of women is at risk:

A

w/o previous/yearly pap smear

27
Q

inflam of endometrium that is MC secondary to pelvic inflam disease or also from retained products internally

A

endometritis

28
Q
  • extrauterine endometrial tissue including ovaries, peritoneum, pouch of douglas, uterine ligs, fallopian tubes, nodes, heart, lungs, etc
  • causes cyclic bleeding and fibrosis
A

endometriosis

29
Q

characteristic of endometriosis

A

chocolate cyst

30
Q

___ is profuse/prolonged menstruation while _____ is irregular spotting bt periods

A

MENOrrhagia

METROrrhagia