ch. 13 - spinal control of movement Flashcards

1
Q

motor system

A

all muscles and the neurons that control them

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2
Q

behavior requires the coordination of how many muscles?

A

almost 700

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3
Q

smooth muscle

A

lines the GI tract, arteries, and related structures; innervated by autonomic nervous system

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4
Q

what is the role of smooth muscles?

A

peristalsis and blood flow

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5
Q

cardiac muscle

A

heart muscle that functions without innervation but can be modified by ANS

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6
Q

skeletal muscle

A

the bulk of muscles mass; muscle within a sheath and composed of hundreds of fibers. innervated by CNS

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7
Q

functions of skeletal muscle

A
  • move bones around joints
  • move eyes within the head
  • control respiration
  • control facial expression
  • produce speech
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8
Q

muscles that work in opposite directions

A

synergists and antagonists

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9
Q

T or F: muscles ONLY pull (shorten), not push

A

true

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10
Q

axial muscles

A

move trunk, posture

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11
Q

proximal muscles

A

move shoulder, elbow, knee, and pelvis - locomotion

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12
Q

distal muscles

A

move fingers, feet, and hands - manipulation of objects

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13
Q

which neurons command muscle contraction?

A

ONLY lower motor neurons

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14
Q

lower motor neurons (LMN)

A

distributed in proportion to skeletal muscle density

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15
Q

LMN controlling flexors are located…

A

dorsal to extensors

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16
Q

LMN controlling axial muscles are located…

A

medial to those controlling distal muscles

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17
Q

which type of LMN triggers muscles?

A

alpha motor neurons

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18
Q

which typer of LMN innervates intrafusal fibers?

A

gamma motor neurons

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19
Q

motor unit

A

one alpha motor neuron and all muscle fibers it innervates

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20
Q

motor neuron pool

A

all alpha motor neurons which innervate a single muscle

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21
Q

what is NT used by alpha motor neurons?

A

acetylcholine (ACh)

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22
Q

how does the CNS grade muscle contraction?

A

by controlling firing rate of motor units and by recruiting more motor units

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23
Q

size principle

A

small motor units have small motor neurons, large have large

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24
Q

are small or large neurons more easily excited?

A

small

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25
Q

twitch

A

rapid sequence of contraction and relaxation

26
Q

“dark meat”

A
  • red muscle fibers
  • slow to contract
  • slow to fatigue
  • present in antigravity muscles
  • many mitochondria
  • use oxidative metabolism
27
Q

“white meat”

A
  • fewer mitochondria
  • anaerobic metabolism
  • rapid
  • powerful
  • fatigue rapidly
  • present in “escape muscle”
28
Q

fast motor units contain

A

white fibers

- 30-60 AP/sec bursts

29
Q

slow motor units contain

A

red fibers

- 10-20 AP/sec steady

30
Q

crossed-innervation experiment

A

muscle switched phenotype to match motor neuron type

31
Q

sarcomere

A

a segment compromised of two Z lines and the myofibril in between

32
Q

myosin

A

major thick filament protein

33
Q

actin

A

major thin filament protein

34
Q

why is Ca2+ required for muscle contraction?

A
  • it initiates contraction by binding to troponin

- contraction continues as long as Ca2+ and ATP are available

35
Q

steps of excitation

A
  1. AP occurs in alpha motor neuron
  2. ACh is released by axon terminal at NMJ
  3. nicotinic receptor channels in sarcolemma open, posysynaptic sarcolemma depolarize (EPSP)
  4. voltage-gated Na+ channels open, AP is generated in muscle fiber, which sweeps down the sarcolemma and into T tubules
  5. depolarization of T tubes causes Ca2+ release from sarcoplasmic reticulum
36
Q

steps of contraction

A
  1. Ca2+ binds to troponin
  2. myosin binding sites on actin are exposed
  3. myosin heads bind actin
  4. myosin heads pivot
  5. myosin heads disengage at the expense of ATP
  6. cycle continues as long asCa2+ and ATP are present
37
Q

steps of relaxation

A
  1. as EPSPs end, the sarcolemma and T tubules return to their rest potentials
  2. Ca2+ is sequestered by sarcoplasmic reticulum by an ATP-driven pump
  3. myosin binding sites on actin are covered by troponin
38
Q

excitation-contraction coupling

A

this AP, excitation, triggers release of Ca2+ from organelle inside muscle fiber, which leads to the contraction of the fiber

39
Q

sliding filament theory

A

process of sacromere shortening when thin filaments slide toward one another on the thick filament

40
Q

muscle spindles

A
  • stretch receptor

- specialized muscle fibers in a fibrous capsule

41
Q

Ia sensory axons

A
  • largest and fastest
  • innervate spindle
  • enter spine at dorsal roots
  • synapse on interneurons and alpha motor neurons
42
Q

proprioception

A

body sense

43
Q

myotatic reflex

A
  • aka stretch reflex

- involves sensory feedback from muscle, shown by cutting the dorsal roots

44
Q

what is an example of myotatic reflex?

A

knee jerk

45
Q

intrafusal fibers

A

modified skeletal fibers within the muscle spindle

46
Q

gamma motor neurons

A
  • innervate intrafusal fibers

- activation keeps the muscle “on air” by contracting the poles of the spindle

47
Q

alpha activation alone..

A

decreases Ia activity

48
Q

gamma activation alone…

A

increases Ia activity

49
Q

circuit of myotatic feedback loop

A

gamma motor neuron to intrafusal muscle fiber to Ia afferent axon to alpha motor neuron to extrafusal fiber

50
Q

golgi tendon organ

A
  • monitors muscle tension or force of contraction

- located in series

51
Q

what innervates golgi tendon organ?

A

Ib sensory neurons

52
Q

reverse myotatic reflex

A
  • keeps muscle from being overloaded
  • muscle tension in optimal range
  • important for manipulation of fragile objects
53
Q

joint receptors

A
  • combined with muscle spindle, golgi tendon organ, and skin receptors
  • rapidly adapting
54
Q

synaptic input from spinal interneurons

A
  • primary sensory axons
  • descending axons from brain
  • collateral of LMN axons
  • other interneurons
55
Q

reciprocal inhibition

A

the contraction of one set of muscles accompanied by the relaxation of the antagonists muscle

56
Q

flexor reflex

A

complex reflex arc used to withdraw limb from adverse stimulus

57
Q

crossed-extensor reflex

A

the activation of extensor muscles and the inhibition of flexor muscles on the OPPOSITE side

58
Q

central patter generators

A

produce rhythmic motor activity

59
Q

rhythms are produced by…

A

pacemaker cells and synaptic connections

60
Q

rhythmic activity steps

A
  1. membrane depolarizes
  2. Na+ and Ca2+ flow into cell through NMDA receptors
  3. Ca2+ activates potassium channels
  4. K+ flows out of cell
  5. membrane hyperpolarizes
  6. Ca2+ stops flowing into cell
  7. potassium channels close
  8. membrane depolarizes, cycle repeats