Cervical cancer Flashcards
1
Q
Types of cervical cancer (2)
A
Squamous (80%)
Adenocarcinoma (20%)
2
Q
Where do most cervical neoplasms arise?
A
The transformation zone between ecto and endocervix
3
Q
precursor lesion to squamous cell carcinoma of cervix
A
cervical intraepithelial neoplasia
4
Q
How is CIN graded?
A
I-III based on depth of mucosa showing neoplastic change
5
Q
Main risk factor for CIN/squamous carcinoma of cervix
A
Persistence of high-risk HPV subtypes 16, 18 and 33
6
Q
Other risk factors for squamous carcinoma of cervix (4)
A
Smoking
COCP
Immunosuppression
Early first intercourse
7
Q
Symptoms of carcinoma of cervix (3)
A
Abnormal bleeding
Pelvic pain
Urinary symptoms (blockage/blood)
8
Q
Treatment of cervical carcinoma?
A
Dependent on stage; early stage likely to be curable with surgery (Wertheim’s hysterectomy)
