Cerebral Cortex Flashcards

1
Q

what is the difference between projection, commissural, and association fibers?

A

projection: ↑↓ - internal capsule

commissural: ⇆ - corpus callosum, anterior commissure

association: within cerebral hemisphere - primary sensory cortex → secondary sensory cortex

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2
Q

cerebral cortex sensory homunculus

A

medial to lateral:
-LE
-trunk
-UE
-face

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3
Q

cerebral cortex motor homunculus

A

medial to lateral:
-LE
-trunk
-UE
-face

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4
Q

cerebral cortex

A

vast collection of cell bodies (gray matter), axons, and dendrites covering the surface of the cerebral hemispheres

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5
Q

what are the layers of the cerebral cortex?

A

molecular layer
external granular layer
external pyramidal layer
internal granular layer
internal pyramidal layer
multiform layer

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6
Q

molecular layer

A
  • mainly axons and dendrites
  • contains few cells
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7
Q

external granular layer

A

many small pyramidal and stellate cells

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8
Q

external pyramidal layer

A

pyramidal cells - long axons

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9
Q

internal granular layer

A

mainly stellate cells

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10
Q

internal pyramidal layer

A

mainly pyramidal cells

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11
Q

multiform layer

A

mainly fusiform cellsm

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12
Q

most of the cerebral cortex has 6 layers, except

A

olfactory and medial temporal cortices - have 3 layers

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13
Q

flow of cortical information from primary sensory cortex to motor output

A

primary sensory cortex → secondary sensory cortex → association cortex → motor planning areas → primary motor cortex

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14
Q

primary sensory cortex

A

simple sensory discrimination (intensity/quality of stimulus)
- somatosensory
- auditory
- visual
- vestibular

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15
Q

primary somatosensory cortex

A

location: parietal lobe - within central sulcus/postcentral gyrus

function: discriminates shape, texture, size of objects

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16
Q

primary auditory cortex

A

location: superior temporal lobe

function: conscious discrimination of intensity of sounds (loudness and pitch )

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17
Q

primary visual cortex

A

location: occipital lobe - calcarine sulcus

function: distinguishes intensity of light, shape, size, location, and movement of objects

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18
Q

primary vestibular cortex

A

location: parietal lobe - Pareto-insular junction

function: discriminates among head positions and movements relative to gravity

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19
Q

secondary sensory cortex

A

recognition of sensation - analyzes sensory input from thalamus and primary sensory cortex

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20
Q

secondary somatosensory cortex

A

-integrates tactile and proprioceptive info obtained from manipulating an object

-provides stereognosis and memory of tactile and spatial environment

-attention, learning, and memory

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21
Q

posterior parietal cortex

A

location: parietal lobe - posterior to secondary somatosensory cortex

function: receives projections from S1, S2, and visual system → highest level of somatosensory processing
- sends outputs to motor system → integrates sensory and motor info, motor planning, and spatial awareness

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22
Q

secondary auditory cortex

A

classifies sounds

contrasts sounds heard from memory and categorizes them

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23
Q

secondary visual cortex

A
  • analyzes color and movements

-output to superior colliculus directs visual fixation, keeping item in central vision

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24
Q

what are the two directions info processed by the secondary visual cortex flow

A

dorsally and ventrally

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25
Q

dorsal stream

A
  • from secondary visual cortex → PCC → frontal lobe

function: action stream - adjusts limbs movements

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26
Q

ventral stream

A

from secondary visual cortex → temporal lobe

function: perception stream - recognizing object

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27
Q

DCML

A

sensory receptor in periphery → DRG → gracile/cuneate in medulla → thalamus → primary somatosensory cortex

28
Q

Spinothalamic tract

A

sensory receptor in periphery → DRG → dorsal horn of SC → thalamus → primary AND SECONDARY somatosensory cortex

29
Q

areas of cortex not directly involved with sensation or movement

A

parietotemporal association cortex

dorsolateral prefrontal cortex

ventral/medial dorsal prefrontal association cortices

30
Q

Temporoparietal association cortex

A
  • INTELLIGENCE
  • wernickes area - language comprehension
  • spatial relationships
31
Q

dorsolateral prefrontal cortex

A

-goal-oriented behavior
-executive functions
- self-awareness

32
Q

ventral dorsal prefrontal association cortex

A

mood and affect
-impulse control, reactions to surroundings

33
Q

medial dorsal prefrontal association cortex

A

perceiving others emotions
-impulse control, reactions to surroundings
- personality

34
Q

motor cortices

A

primary motor
premotor
supplemental motor

35
Q

primary motor cortex

A

location: pre central gyrus of frontal lobe

execution
fractionated movement

36
Q

lesion to primary motor cortex results in

A

contralateral weakness/paresis

contralateral loss of fractionated movement

dysarthria

NO SPASTICITY

37
Q

premotor cortex

A

location: anterior to primary motor cortex (lateral to supplementary cortex)

motor planning
anticipatory postural adjustments

38
Q

lesion to premotor cortex results in

A

inability to plan movement or have anticipatory postural adjustments
- spasticity

39
Q

supplementary motor area

A

location: anterior to primary motor cortex (medial to premotor cortex)

movement initiation
sequential movements

40
Q

lesion to supplementary motor area results in

A

acutely: contralateral weakness/paresis

chronic: inability to perform anti-phase movements

41
Q

motor perseveration

A

uncontrolled repetition of movement

42
Q

apraxia/dyspraxia

A

inability to perform movement sequence despite intact sensation, normal muscle coordination, and understanding the task
- lesion to premotor cortex, supplementary motor areal or inferior parietal lobe

43
Q

what are the 4 types of apraxia

A

constructional
ideational
ideomotor
gait apraxia

44
Q

contructional apraxia

A

interferes with ability to comprehend the relationship pf parts to the whole
- difficulty determining how to arrange objects correctly in space

45
Q

ideational apraxia

A

inability to use objects appropriately, especially when sequence is necessary

46
Q

ideomotor apraxia

A

classic apraxia

inability to develop movement sequence, especially to command or mimic activity

47
Q

gait apraxia

A

“magnetic gait”

abnormal gait characterized by slow, shuffling steps where feet barely lift from ground, making it difficult to initiate walking

48
Q

astereognosis

A

inability to identify objects by touch/manipulation but with an intact discriminative somatosensation → can feel object, but cannot recognize it

49
Q

visual agnosia

A

inability to visually recognize objects despite having intact vision
- disorder of ventral visual stream

50
Q

prospoagnosia

A

inability to visually identify peoples faces
- damage to inferior secondary visual cortex

51
Q

auditory agnosia

A

can hear sounds, but cannot recognize sounds

52
Q

lesion to L secondary auditory cortex →

A

unable to UNDERSTAND speech

53
Q

lesion t o R secondary auditory cortex →

A

inability to interpret environmental sounds
- cannot differentiate between fire alarm and door bell

54
Q

anosagnosia

A

inability to recognize deficits
- lesion to R anterior ínsula

55
Q

homonymous hemisanopsia

A

lesion of optic tract → loss of info from contralateral visual field

R lesion → loss of L temporal and R nasal vision

56
Q

optic ataxia

A

inability to use visual info to direct movements
- intact ability to visually identify objects
- damage to dorsal visual stream

57
Q

hemineglect

A

inability to attend to objects, or even their own body, in portion of space, despite intact visual acuity, somatic sensation, motor ability
- 1 side their body/world does not exist
- lesion to R PPC

58
Q

what is the difference between hemineglect and pusher syndrome

A

neglect: R lesion → L neglect → R shift
-push to contralateral side

pusher syndrome: R lesion → L impaired → L shift
- push to ipsilateral side

59
Q

what are the 4 A’s for cerebral cortex disorders

A

aphasia
apraxia
agnosia
astereognosis

60
Q

epilepsy

A

sudden burst of excessive cortical neuronal discharge (electrical activity) interfering with brain function

61
Q

general versus partial seizures

A

general: affected ENTIRE cortex

partial: affect RESTRICTED area of cortex

62
Q

absence seizures

A

brief loss of consciousness without motor manifestations

63
Q

tonic-clonic seizures

A

start with tonic contraction of skeletal muscles followed by alternating contraction/relaxation of muscles

64
Q

functional neurological disorders

A
  • disorder of communication across and range of brain networks
  • conditions where people experience real neurological symptoms (like weakness, tremors, seizures, or sensory changes), but no structural neurological disease explains them. It’s a disruption in nervous system functioning, not damage.
65
Q

Hoover sign

A

weak hip extension initially, but when then with contralateral sitting hip flexion, hip extensors strong

66
Q

give-way weakness

A

strong but then abrupt collapse (without pain)

67
Q

whack a mole sign

A

if you restrain a tremor in a body part, it surfaces in another