Cerebellum part 2 Flashcards
medial longitudinal fasiculus (MLF)
vestibular nucleus sends axons thru MLF to CN III, IV, VI
nuclei
axons sent thru MLF to CN III, IV, VI
nuclei
bilateral in
Vestibulocerebellar System
mooth pursuit
allows the eyes to follow a moving stimulus (maintains the stimulus on the fovea)
needs the cerebllum
smooth pursuit
Cortical eye fields –>vest nuclei–> Cb –> vestibular nucleus –> CN III, IV, VI nuclei via the MLF
Cortical eye fields –> pontine nuclei –> Cb –> vestibular nucleus –> CN III, IV, VI nuclei via the MLF
The cerebellum compares the—– ——with the intended movement and ——– the required corrections to maintain —— and proper eye position .
The cerebellum compares the vestibular input with the intended movement and “computes” the required corrections to maintain equilibrium and proper eye position .
Generalized loss of equilibrium
Lesion of the Vestibulocerebellum
Impaired ability to coordinating eye movements with head movements
Lesion of the Vestibulocerebellum
Altered output along medial vestibulospinal tract – Altered output along MLF
Lesion of the Vestibulocerebellum
Carries proprioceptive information trunk & LEs (T1 and below)
tPosterior Spinocerebellar Tract
tCuneocerebellar Tract
Carries proprioceptive information neck & UEs (rostral to T1)
Anterior Spinocerebellar Tract
proprioceptive information and cutaneous information
from receptors with large receptive fields from LEs
Carries proprioceptive information from the oral cavity
Trigeminocerebellar Tract
Propriceptive afferents travel in dorsal column
of Posterior Spinocerebellar Tract and travel to
Clarke’ s Column T1 - L2
Axons travel superiorly within the
posterior spinocerebellar tract

Posterior spinocerebellar tract travels thru
Inferior cerebellar peduncle
tf Posterior Spinocerebellar Tract only travel to vermis
F vermis and paravermis
TF Cuneocerebellar Tract
Axons travel in the dorsal column (fasciculus cuneatus) to med/ internal/ accessory cuneate nucleus
Cuneocerebellar Tract
Axons travel in the dorsal column (fasciculus cuneatus) to Lateral/ external/ accessory cuneate nucleus
TF Cuneocerebellar Tract uses Clarke’s Column T1 - L2
F
propriceptive afferents from C1-C8
Cuneocerebellar Tract
Ipsilateral
Cuneocerebellar Tract
Posterior Spinocerebellar Tract
travels contralat then contralat back to same side
(after ascending)
Anterior Spinocerebellar Tract
Superior cerebellar peduncle
Anterior Spinocerebellar Tract
fibers
both use Inferior cerebellar peduncle
Cuneocerebellar Tract
Posterior Spinocerebellar Tract
Primary afferents synapse on spinal border cells (T2-L5)
Anterior Spinocerebellar Tract
Trigeminocerebellar Tract
Proprioceptive info carried along branches of CN-V (ie. muscles of mastication, periodontal ligament)
Proprioceptive info carried along branches of CN-V (ie. muscles of mastication, periodontal ligament) carried to
trigerm. cerebellar tract
spinal trigeminal nucleus.
Axons from the spinal trigeminal nucleus project to the cerebellum
trigem cereblar tract
via the inferior cerebellar peduncle.
trigeminoceebellar tract
cerebellum influences motor output by projecting to the
trigeminal motor nucleus.
This circuit allow the oral motor system to receive —— ——— during mastication
trgemcerebellar tract
This circuit allow the oral motor system to receive continual feedback during mastication
The cerebellum monitors the —— ——- on muscles of mastication and influences —— output accordingly.
trigem. cerebllar tract
The cerebellum monitors the changing demands on muscles of mastication and influences motor output accordingly.
(ant post)Spinocerebellar and Trigeminocerebellar Tract
functions
After processing proprioceptive information in cerebellum , cerebellar efferents project to motor regions, either directly or indirectly via the thalamus.
allows for adjustment of movement during ongoing movement
Functions Spinocerebellar and Trigeminocerebellar Tracts
The cerebellum compares the intended movement with the actual movement and “computes” the required corrections.
Efferent projections from the cerebellum corrects the movement
Corticospinal tract and Rubrospinal tract
act modulate motor output in the Spinocerebellar System in the Proprioceptive afferents responce
synapse in red nucleus
Rubrospinal tract efferent responce
contralateral to the skeletal muscle
Corticospinal tract and Rubrospinal tract
(Spinocerebellar System afferent responce)
Impaired ability to control axial muscles/ impaired trunk control
Lesion of the Spinocerebellum
Altered rate, range, accuracy of limb movements
Lesion of the Spinocerebellum
Dysmetria (overshooting a target)
lead to Intention Tremor
in Lesion of the Spinocerebellum
and inLesion to the Cerebrocerebellum
Dysmetria
Rely on the feed-back
inf olive role in cerebrocellebellar tract
recieves input from dentate(from cerebellar hemisphere)
then has to correct and send climbing fibers to lat hemisphere of cerebellum
Receives extensive input from the cerebral cortex (via pontine nuclei)
cerebellum in the
Cerebrocerebellar System
Involved in the planning, initiation, timing and control of motor movements.
cerebellum
VA/VL
recieves neurons from dentate
and sends neurons to motor cortex to modulate activity
Pontine nuclei
recieves infor fromcerebral cortex and sends info to lateral hemishphere of Cerebelum
climbing fibers
goes thru Inferior cerebellar peduncle to cerebellum(lat hemisphere)
Middle cerebellar peduncle
carries axons from pontne nucleus to lat cerebellum
contralat
Corticospinal and Rubrospinal Tracts
The cerebellar hemisphere compares the —- movement with the —– movement and “computes” the required corrections for the next time the task is performed.
The cerebellar hemisphere compares the intended movement with the actual movement and “computes” the required corrections for the next time the task is performed.
—— projections from the cerebellum corrects the movement via the —– tract.
Efferent projections from the cerebellum corrects the movement via the corticospinal tract.
Studies on non-human primates
reversible cooling in the —– nucleus resulted in delayed —– of movement.
reversible cooling in the dentate nucleus resulted in delayed onset/initiation of movement.
Lesion to the Cerebrocerebellum
Movement takes place —– rather than being coordinated smoothly
Lesion to the Cerebrocerebellum
Impaired ability to plan motor movement
seen with inactivating the interposed [globos/emboliform] in monkeys
Lesion to the Cerebrocerebellum