Cerebellum Flashcards

1
Q

List 4 functions of cerebellum?

A

1) Maintenance of posture and balance
2) Maintenance of muscle tone
3) Coordination of voluntary movements
4) Precise control, fine adjustment & coordination of motor activity

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2
Q

What is responsible for co-ordination of voluntary movements?

A

Cerebellum

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3
Q

Label

A
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4
Q

Where is cerebellum?

A

Posterior cranial fossa

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5
Q

What 3 lobes cerebellum?

A

Superior
Middle
Inferior

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6
Q

What covers cerebellum?

A

Cerebellar cortex
3 layers

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7
Q

What are 3 layers of cerebellar cortex?

A

Molecular (outside)
Purkinje (middle)
Granule (inner)

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8
Q

What is outside layer of cerebellar cortex?

A

Molecular

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9
Q

What is inner layer of cerebellar cortex?

A

Granule

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10
Q

What 2 types neurons present in molecular layer of cerebellar cortex? What function

A

Stellate (GABA)
Basket

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11
Q

Which layer of cerebellar cortex provides efferent pathway to cerebellum?
Input

A

Purkinje- efferent- away CNS
Climbing fibres

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12
Q

Which layer of cerebellar cortex receives input from mossy fibres?

A

Granule
Mossy

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13
Q
A
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14
Q

What are 2 inputs in cerebellar cortex?

A

Mossy fibres
Climbing fibres

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15
Q

Where peduncle are mossy fibres present? (middle)
Afferents or efferent
End?
Neurotrans- excite or inhib?

A

All afferents except inferior olivary nuclei
End granule layer
Glutamergic- excitatory

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16
Q

Are mossy fibres Inhib or excit?
Neurotrans

A

Glutamatergic- excitatory

17
Q

Location of climbing fibres?
originate?
Excite or inhib to what?
End?
Neurotrans?

A

Inferior peduncle
Inferior olivary nucleus
Excitatory input to purkinje fibres
End molecular layer
Glutamatergic- excitatory

18
Q

What information do climbing fibres carry?

A

Proprioception and vestibular system

19
Q

What information do mossy fibres carry?

A

Pontocerebellar pathway

20
Q

What is output from cerebellar cortex?

A

Purkinje cell axons

21
Q

State pathway purkinje cell axons out cerebellar cortex?

A

1) Dentate nucleus
2) Superior peduncle and decussate
3) Thalamus and red nucleus

22
Q

What neurotransmitter do purkinje cell axons use?

A

GABA inhibition

23
Q

What occurs when cerebellar damaged?

A

DANISH
Dysdiadochokinesia- inability to perform rapidly alternating
movements
Ataxia- effect balance and speech
Nystagmus- eye movement abnormal
Intension tremor (movement tremor)
Slurred speech
Hypertonia- weak muscles

24
Q

What is DANISH caused by?

A

Cerebellar dysfunction- bilateral hemispheric lesions