Cerebellum Flashcards
List 4 functions of cerebellum?
1) Maintenance of posture and balance
2) Maintenance of muscle tone
3) Coordination of voluntary movements
4) Precise control, fine adjustment & coordination of motor activity
What is responsible for co-ordination of voluntary movements?
Cerebellum
Label
Where is cerebellum?
Posterior cranial fossa
What 3 lobes cerebellum?
Superior
Middle
Inferior
What covers cerebellum?
Cerebellar cortex
3 layers
What are 3 layers of cerebellar cortex?
Molecular (outside)
Purkinje (middle)
Granule (inner)
What is outside layer of cerebellar cortex?
Molecular
What is inner layer of cerebellar cortex?
Granule
What 2 types neurons present in molecular layer of cerebellar cortex? What function
Stellate (GABA)
Basket
Which layer of cerebellar cortex provides efferent pathway to cerebellum?
Input
Purkinje- efferent- away CNS
Climbing fibres
Which layer of cerebellar cortex receives input from mossy fibres?
Granule
Mossy
What are 2 inputs in cerebellar cortex?
Mossy fibres
Climbing fibres
Where peduncle are mossy fibres present? (middle)
Afferents or efferent
End?
Neurotrans- excite or inhib?
All afferents except inferior olivary nuclei
End granule layer
Glutamergic- excitatory
Are mossy fibres Inhib or excit?
Neurotrans
Glutamatergic- excitatory
Location of climbing fibres?
originate?
Excite or inhib to what?
End?
Neurotrans?
Inferior peduncle
Inferior olivary nucleus
Excitatory input to purkinje fibres
End molecular layer
Glutamatergic- excitatory
What information do climbing fibres carry?
Proprioception and vestibular system
What information do mossy fibres carry?
Pontocerebellar pathway
What is output from cerebellar cortex?
Purkinje cell axons
State pathway purkinje cell axons out cerebellar cortex?
1) Dentate nucleus
2) Superior peduncle and decussate
3) Thalamus and red nucleus
What neurotransmitter do purkinje cell axons use?
GABA inhibition
What occurs when cerebellar damaged?
DANISH
Dysdiadochokinesia- inability to perform rapidly alternating
movements
Ataxia- effect balance and speech
Nystagmus- eye movement abnormal
Intension tremor (movement tremor)
Slurred speech
Hypertonia- weak muscles
What is DANISH caused by?
Cerebellar dysfunction- bilateral hemispheric lesions
