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USMLE Step I > Cell Surface Markers > Flashcards

Cell Surface Markers Flashcards

1
Q

CD64

A

monocytic antigen

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2
Q

CD14

A

monocytic antigen

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3
Q

CD41

A

megakaryoblastic antigen

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4
Q

CD61

A

megakaryoblastic antigen

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5
Q

CD34

A

marker of immaturity in lymphoblasts and myeloblasts

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6
Q

TdT

A

immature lymphoblasts (nuclear enzyme)

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7
Q

CD19

A

B lineage antigen

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8
Q

CD22

A

B lineage antigen

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9
Q

CD79a

A

B lineage antigen

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10
Q

CD20

A

Mature B cell marker

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11
Q

CD2

A

T cell lineage antigen

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12
Q

CD3

A

T cell lineage antigen

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13
Q

CD7

A

T cell lineage antigen

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14
Q

CD99

A

T cell lineage antigen

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15
Q

CD1a

A

T cell lineage antigen

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16
Q

CD117

A

aka c-kit, Myeloid antigen (blasts)

17
Q

myeloperoxidase

A

Myeloid antigen (blasts)

18
Q

CD33

A

Myeloid antigen (blasts)

19
Q

CD13

A

Myeloid antigen (blasts)

20
Q

CD5

A

Found on T cells and IgM secreting B cells

21
Q

CD23

A

Found on mature B cells, activated macrophages, eosinophils, follicular dendritic cells, and platelets.

22
Q

CD19

A

Follicular dendritic cells and B cell lineage from earliest recognizable B-lineage cells to blasts but is lost on plasma cells.

23
Q

CD22

A

Mature B cells and to a lesser extent B lineage.

24
Q

CD10

A

marker for ALL, Burkitt lymphoma, and follicular germinal center lymphoma. Normally present on early lymphoid cells and other normal cells, such as kidney.

25
CD11C
high levels on most dendritic cells, but also on monocytes, macrophages, neutrophils, and some B cells, expressed in hairy cell leukemias, acute nonlymphocytic leukemias, and some B-cell chronic lymphocytic leukemias.
26
FMC7
Epitope of CD20
27
CD38
Marker of poor prognosis for CLL/SLL
28
Zap70
Marker of poor prognosis for CLL/SLL
29
BCL6
Marker of actively dividing germinal center (follicular) B cells.
30
M protein
Single immunoglobulin marker secreted by plasma cell neoplasms.
31
CD15
Present on almost all Reed–Sternberg cells, and some others.
32
CD30
Common marker on Reed-Sternberg Cells

USMLE Step I (25 decks)

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