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USMLE Step I > Cell Surface Markers > Flashcards

Cell Surface Markers Flashcards

1
Q

CD64

A

monocytic antigen

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2
Q

CD14

A

monocytic antigen

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3
Q

CD41

A

megakaryoblastic antigen

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4
Q

CD61

A

megakaryoblastic antigen

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5
Q

CD34

A

marker of immaturity in lymphoblasts and myeloblasts

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6
Q

TdT

A

immature lymphoblasts (nuclear enzyme)

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7
Q

CD19

A

B lineage antigen

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8
Q

CD22

A

B lineage antigen

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9
Q

CD79a

A

B lineage antigen

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10
Q

CD20

A

Mature B cell marker

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11
Q

CD2

A

T cell lineage antigen

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12
Q

CD3

A

T cell lineage antigen

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13
Q

CD7

A

T cell lineage antigen

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14
Q

CD99

A

T cell lineage antigen

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15
Q

CD1a

A

T cell lineage antigen

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16
Q

CD117

A

aka c-kit, Myeloid antigen (blasts)

17
Q

myeloperoxidase

A

Myeloid antigen (blasts)

18
Q

CD33

A

Myeloid antigen (blasts)

19
Q

CD13

A

Myeloid antigen (blasts)

20
Q

CD5

A

Found on T cells and IgM secreting B cells

21
Q

CD23

A

Found on mature B cells, activated macrophages, eosinophils, follicular dendritic cells, and platelets.

22
Q

CD19

A

Follicular dendritic cells and B cell lineage from earliest recognizable B-lineage cells to blasts but is lost on plasma cells.

23
Q

CD22

A

Mature B cells and to a lesser extent B lineage.

24
Q

CD10

A

marker for ALL, Burkitt lymphoma, and follicular germinal center lymphoma. Normally present on early lymphoid cells and other normal cells, such as kidney.

25
Q

CD11C

A

high levels on most dendritic cells, but also on monocytes, macrophages, neutrophils, and some B cells, expressed in hairy cell leukemias, acute nonlymphocytic leukemias, and some B-cell chronic lymphocytic leukemias.

26
Q

FMC7

A

Epitope of CD20

27
Q

CD38

A

Marker of poor prognosis for CLL/SLL

28
Q

Zap70

A

Marker of poor prognosis for CLL/SLL

29
Q

BCL6

A

Marker of actively dividing germinal center (follicular) B cells.

30
Q

M protein

A

Single immunoglobulin marker secreted by plasma cell neoplasms.

31
Q

CD15

A

Present on almost all Reed–Sternberg cells, and some others.

32
Q

CD30

A

Common marker on Reed-Sternberg Cells

USMLE Step I (25 decks)

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