Cell Surface Markers Flashcards
CD64
monocytic antigen
CD14
monocytic antigen
CD41
megakaryoblastic antigen
CD61
megakaryoblastic antigen
CD34
marker of immaturity in lymphoblasts and myeloblasts
TdT
immature lymphoblasts (nuclear enzyme)
CD19
B lineage antigen
CD22
B lineage antigen
CD79a
B lineage antigen
CD20
Mature B cell marker
CD2
T cell lineage antigen
CD3
T cell lineage antigen
CD7
T cell lineage antigen
CD99
T cell lineage antigen
CD1a
T cell lineage antigen
CD117
aka c-kit, Myeloid antigen (blasts)
myeloperoxidase
Myeloid antigen (blasts)
CD33
Myeloid antigen (blasts)
CD13
Myeloid antigen (blasts)
CD5
Found on T cells and IgM secreting B cells
CD23
Found on mature B cells, activated macrophages, eosinophils, follicular dendritic cells, and platelets.
CD19
Follicular dendritic cells and B cell lineage from earliest recognizable B-lineage cells to blasts but is lost on plasma cells.
CD22
Mature B cells and to a lesser extent B lineage.
CD10
marker for ALL, Burkitt lymphoma, and follicular germinal center lymphoma. Normally present on early lymphoid cells and other normal cells, such as kidney.
CD11C
high levels on most dendritic cells, but also on monocytes, macrophages, neutrophils, and some B cells, expressed in hairy cell leukemias, acute nonlymphocytic leukemias, and some B-cell chronic lymphocytic leukemias.
FMC7
Epitope of CD20
CD38
Marker of poor prognosis for CLL/SLL
Zap70
Marker of poor prognosis for CLL/SLL
BCL6
Marker of actively dividing germinal center (follicular) B cells.
M protein
Single immunoglobulin marker secreted by plasma cell neoplasms.
CD15
Present on almost all Reed–Sternberg cells, and some others.
CD30
Common marker on Reed-Sternberg Cells
