Cell Junctions Flashcards

1
Q

Direct attach between cells are made by

A

Cell-cell junctions

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

Cell junctions are more abundant in (5)

A
Epithelial tissue
Connective tissue
Cardiac muscle 
Smooth muscle
Nervous tissue
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

What types of junctions are in cell to cell junctions (3)

A

Tight junctions
Cell-cell anchoring junctions
Gap junctions

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

What types of junctions are in cell to matrix junctions

A

Cell matrix anchoring junctions

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

What are the cell to cell anchoring junctions (2)

A

Adherens junctions

Desmosome

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

What are in the cell to matrix anchoring junctions

A

Actin linked cell matrix junctions

Hemidesmosome

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

Tight junctions are (3)

A

Seal gap between epithelial cells
Most apical location
Found in epithelial cells

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

Where are tight junctions found

A

Epithelial cells
In lining intestinal mucous
Bladder
Etc.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

Tight junctions do

A

Seal intercellular space from Lumina environment

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

What does it mean that tight junctions are not absolute

A

Means that their permeable to ions and other small molecules but not to macromolecules

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

What are the proteins used in tight junctions

A

Claudine and occulin

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

Cell to cell junctions depend on

A

Cadherin

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

Cadherin does what

A

Span the plasma membrane, with one end linking to the Cytoskeleton and the other end linking to structures outside of it

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

Adherence junctions are a type of

A

Cell to cell anchoring junctions

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

Adherence junctions are

A

Intermediate junctions or adhesion belt
Connect actin filament bundle of one cell to the ones in another cell
More basal than tight junction

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

Adherence junctions are found in

A

Epithelial cells
Cardiac muscle
Fibroblasts

17
Q

What do adherence junctions provide to cytoskeleton

A

Anchorage site for cytoskeleton

18
Q

Help modeling the shape of multicellular structures
Guides the organization of developing tissues
Important in tissue remodeling

A

Adherence junctions

19
Q

What are desmosomes

A

Type of cell to cell adherence anchoring junction

20
Q

What to desmosomes do (3)

A

Connect intermediate filaments from one cell to those in another
Provide anchorage site for cytoskeleton
Main function to provide mechanical strength

21
Q

What is the main function of a desmosome

A

Provide mechanical strength

22
Q

Where are desmosomes located

A

In tissues that suffer a lot of stress/stretch like skin intestine, stomach, bladder, etc

23
Q

Gap junctions are a type of

A

Cell to cell junction

24
Q

Gap junctions allow

A

The passage of small water soluble molecules from cell to cell without having to pass through the plasma membrane

25
Gap junctions are found where 3
Connective tissue Epithelial tissue Cardiac muscle Etc
26
What are integrins
Transmembrane proteins
27
Cell to matrix junctions depend on
Integrins
28
Cell to matrix junctions are activated when
After binding Extracellular matrix legends or intercellular activator proteins
29
Cell to matrix produce
Intracellular signals that can influence almost any aspects cell behavior like proliferation, survival, polarity, or migration)
30
Cell to matrix anchoring junctions are 2
Actin linked cell matrix junction | Hemidesmosomes
31
Actin linked junctions are also known as
Focal adhesion
32
Actin linked junctions do what
Anchors actin filaments in cell to Extracellular matrix
33
Actin linked junctions can be
Small and transient | Large and durable
34
Hemidesmosomes anchor? Using?
Intermediate filaments in a cell to Extracellular matrix using integrins
35
Hemidesmosomes are found where
Epithelial cells connecting basal face of the basal lamina