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Cellular Biology > Cell Junctions > Flashcards

Cell Junctions Flashcards

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1
Q

Direct attach between cells are made by

A

Cell-cell junctions

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2
Q

Cell junctions are more abundant in (5)

A 
Epithelial tissue
Connective tissue
Cardiac muscle 
Smooth muscle
Nervous tissue
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3
Q

What types of junctions are in cell to cell junctions (3)

A

Tight junctions
Cell-cell anchoring junctions
Gap junctions

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4
Q

What types of junctions are in cell to matrix junctions

A

Cell matrix anchoring junctions

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5
Q

What are the cell to cell anchoring junctions (2)

A

Adherens junctions

Desmosome

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6
Q

What are in the cell to matrix anchoring junctions

A

Actin linked cell matrix junctions

Hemidesmosome

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7
Q

Tight junctions are (3)

A

Seal gap between epithelial cells
Most apical location
Found in epithelial cells

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8
Q

Where are tight junctions found

A

Epithelial cells
In lining intestinal mucous
Bladder
Etc.

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9
Q

Tight junctions do

A

Seal intercellular space from Lumina environment

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10
Q

What does it mean that tight junctions are not absolute

A

Means that their permeable to ions and other small molecules but not to macromolecules

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11
Q

What are the proteins used in tight junctions

A

Claudine and occulin

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12
Q

Cell to cell junctions depend on

A

Cadherin

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13
Q

Cadherin does what

A

Span the plasma membrane, with one end linking to the Cytoskeleton and the other end linking to structures outside of it

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14
Q

Adherence junctions are a type of

A

Cell to cell anchoring junctions

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15
Q

Adherence junctions are

A

Intermediate junctions or adhesion belt
Connect actin filament bundle of one cell to the ones in another cell
More basal than tight junction

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16
Q

Adherence junctions are found in

A

Epithelial cells
Cardiac muscle
Fibroblasts

17
Q

What do adherence junctions provide to cytoskeleton

A

Anchorage site for cytoskeleton

18
Q

Help modeling the shape of multicellular structures
Guides the organization of developing tissues
Important in tissue remodeling

A

Adherence junctions

19
Q

What are desmosomes

A

Type of cell to cell adherence anchoring junction

20
Q

What to desmosomes do (3)

A

Connect intermediate filaments from one cell to those in another
Provide anchorage site for cytoskeleton
Main function to provide mechanical strength

21
Q

What is the main function of a desmosome

A

Provide mechanical strength

22
Q

Where are desmosomes located

A

In tissues that suffer a lot of stress/stretch like skin intestine, stomach, bladder, etc

23
Q

Gap junctions are a type of

A

Cell to cell junction

24
Q

Gap junctions allow

A

The passage of small water soluble molecules from cell to cell without having to pass through the plasma membrane

25
Q

Gap junctions are found where 3

A

Connective tissue
Epithelial tissue
Cardiac muscle
Etc

26
Q

What are integrins

A

Transmembrane proteins

27
Q

Cell to matrix junctions depend on

A

Integrins

28
Q

Cell to matrix junctions are activated when

A

After binding Extracellular matrix legends or intercellular activator proteins

29
Q

Cell to matrix produce

A

Intracellular signals that can influence almost any aspects cell behavior like proliferation, survival, polarity, or migration)

30
Q

Cell to matrix anchoring junctions are 2

A

Actin linked cell matrix junction

Hemidesmosomes

31
Q

Actin linked junctions are also known as

A

Focal adhesion

32
Q

Actin linked junctions do what

A

Anchors actin filaments in cell to Extracellular matrix

33
Q

Actin linked junctions can be

A

Small and transient

Large and durable

34
Q

Hemidesmosomes anchor? Using?

A

Intermediate filaments in a cell to Extracellular matrix using integrins

35
Q

Hemidesmosomes are found where

A

Epithelial cells connecting basal face of the basal lamina

Cellular Biology (13 decks)

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