Cell Division/Cell Aging and Death Flashcards

1
Q

What are the three stages of interphase?

A

G1, S, and G2

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2
Q

G1

A

growth and preparation for DNA replication

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3
Q

S phase (synthesis)

A

DNA replication

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4
Q

G2

A

growth and preparation for division of DNA

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5
Q

What are the phases of mitosis?

A

prophase, metaphase, anaphase, and telophase

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6
Q

Prophase

A
  • nucleus breaks
  • chromatin coils up into chromosome
  • spindle fibers appear
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7
Q

Metaphase

A
  • chromosomes line up in the middle of the cell
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8
Q

Anaphase

A
  • chromatid begins moving apart towards the cell’s poles
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9
Q

Telophase

A
  • Chromosomes begin to relax
  • Cleavage is formed
  • Nucleus is reformed
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10
Q

What does “pro-“ mean?

A

prepare

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11
Q

What does “meta-“ mean?

A

middle

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12
Q

What does “telo-“ mean?

A

end

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13
Q

Which to cell cycle phases overlap?

A

cytokinesis and telophase

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14
Q

DNA replication is also known as what?

A

DNA synthesis

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15
Q

DNA replication steps

A
  1. Parent DNA
  2. Parent strands unzipped
  3. Complementary strands synthesized
  4. 2 “sister” DNA copies
  5. Chromosome
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16
Q

What are the parts of a chromosome?

A

2 sister chromatids and centromere

17
Q

Chromatids

A

each of the two threadlike strands into which a chromosome divides longitudinally during cell division.

18
Q

What does each chromatid contain?

A

a double helix of DNA

19
Q

Centromere

A

the region of a chromosome to which the microtubules of the spindle attach

20
Q

What does DNA replication require?

A

regulatory proteins

21
Q

What is an example of regulatory proteins?

A

DNA polymerase matches with 50 nucleotides

22
Q

What do occasional mistakes in DNA replication?

A

mutations

23
Q

Mutations

A

random changes in DNA

24
Q

The cell cycle is typically what kind of process?

A

highly controlled

25
Q

What is the result of disrupted cell regulation?

A

uncontrolled division

26
Q

What is the result of uncontrolled division?

A

tumors

27
Q

What are the two kinds of tumors?

A

benign and malignant

28
Q

Benign tumors (noncancerous)

A

tend to grow slowly and do not spread

29
Q

Malignant tumors (cancerous)

A

can grow rapidly, invade and destroy nearby normal tissues, and spread throughout the body

30
Q

What are the two types of cell death?

A

necrosis and apoptosis

31
Q

Necrosis

A

killed ny harmful agents/mechanical damage

32
Q

What is the problem with necrosis?

A

with cellular lysis, the messy contents of the cell spills into the body

33
Q

Cellular lysis causes what?

A

inflammation (swelling, redness, and pain)

34
Q

Apoptosis

A

programmed cell death

35
Q

What are the goals of apoptosis?

A

removal of damaged cells and normal development

36
Q

What is an example of apoptosis’s role in normal development?

A

removing the tail of the human embryo

37
Q

What are the steps involved in apoptosis?

A
  1. destruction of DNA/organelles
  2. breaking into vesicles so that the contents doe not spill
38
Q

What happens to the contents in the vesicles formed in apoptosis?

A

it is recycled by macrophages

39
Q

What does “-phage” mean?

A

eat