Cell cycle (cytokinesis) Flashcards

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1
Q

final stage in the cell cycle

A

cytokinesis

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2
Q

division of the cytoplasm in two.

A

cytokinesis

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3
Q

some cells undergo ____without cytokinesis and thereby acquire multiple nuclei.

A

mitosis

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4
Q

The first visible change of cytokinesis in an animal cell

A

appearance of a pucker, or cleavage furrow

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5
Q

The structure underlying furrow process

A

contractile ring

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6
Q

As the sister chromatids separate in anaphase, ____ and _____ II begin to
accumulate in the rapidly assembling
contractile ring

A

actin and myosin II

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7
Q

depends on formin (parallel arrays of
linear, unbranched actin filaments)

A

local formation of actin filaments

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8
Q

overlapping arrays of actin and myosin II
filaments ___ to generate the force
that divides the cytoplasm in two

A

contract

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9
Q

persists as a tether between
the two daughter cells and contains the
remains of the central spindle

A

midbody

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10
Q

a large protein structure derived from
the antiparallel interpolar microtubules
of the spindle midzone, packed tightly
together within a dense matrix material

A

central spindle

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11
Q

small GTPase of the Ras superfamily

A

RhoA

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12
Q

controls the assembly and function of the
contractile ring at the site of cleavage

A

RhoA

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13
Q

RhoA promotes:

A

actin filament formation, myosin II
assembly, and ring contraction at the cell
cortex

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14
Q

RhoA stimulates actin filament formation by

A

activating formins; activating multiple protein
kinase (Rock)

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15
Q

must occur only after the two sets of
chromosomes are fully segregated from each other

A

Cytokinesis

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16
Q

must be placed
between the two sets of daughter
chromosomes

A

site of division

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17
Q

depend on
mitotic spindle

A

correct timing and position

18
Q

during anaphase, the spindle generates
signals that initiate ____ formation at a
position midway between the ____
___

A

furrow
spindle poles

19
Q

Why cytokinesis also occurs
at the correct time

A

because dephosphorylation of Cdk substrates, which depends on cyclin destruction in metaphase and anaphase, initiates cytokinesis

20
Q

How does the mitotic spindle specify the site of division?

A
  1. astral stimulation model
  2. central spindle stimulation model
  3. astral relaxation model
21
Q

astral microtubules carry furrow-inducing
signals

A

astral stimulation model

22
Q

the spindle midzone, or central spindle,
generates a furrow
-inducing signal that
specifies the site of furrow formation at
the cell cortex

A

central spindle stimulation model

23
Q

the astral microtubules promote the
local relaxation of actin
–myosin bundles
at the cell cortex

A

astral relaxation model

24
Q

cortical relaxation is minimal at the
spindle equator; promoting cortical
contraction

A

astral relaxation model

25
Q

higher-plant cells are enclosed by a semirigid

A

cell wall

26
Q

the cytoplasm of the plant cell is _____from the ____out by the _____ __ _ ___ ___ ____, called
the cell plate, between the two daughter nuclei

A

partitioned
inside
construction of a new cell wall ( cell plate)

27
Q

The assembly of the
cell plate begins in

A

late anaphase and is guided by a structure called the phragmoplast

28
Q

contains microtubules derived from the mitotic spindle

A

phragmoplast

29
Q

each daughter cell must also inherit all of the other essential cell
components, including the membrane-enclosed organelles

A

process of mitosis

30
Q

can arise only by the growth and division of the preexisting
organelles.

A

organelles

31
Q

usually present in large
enough numbers;their numbers double once each cycle

A

mitochondria and chloroplasts

32
Q

cut into two during cytokinesis

A

ER

33
Q

reorganized and fragmented during mitosis

A

Golgi apparatus

34
Q

cells divide asymmetrically to produce
two cells that ____ in size, in the
cytoplasmic contents they inherit, or in
both

A

different

35
Q

the mother cell must first segregate ___ _____ _______ to one side of the cell
and then position the ___of ____
so that the appropriate daughter cell
inherits these components

A

cell fate determinants
plane of division

36
Q

Some cells undergo multiple rounds of nuclear division without intervening _____ division.

A

cytoplasmic

37
Q

first 13 rounds of nuclear division occur without cytoplasmic division

A

Drosophila embryo

38
Q

A cell in which multiple nuclei share the same
cytoplasm is called a

A

syncytium

39
Q

greatly speeds up early development

A

syncytium

40
Q

membranes are created around each nucleus
in one round of coordinated cytokinesis

A

cellularization

41
Q

Nuclear division without cytokinesis in some types of mammalian
cells

A

megakaryocytes, hepatocytes, heart muscle cells

42
Q
A