Cell Cycle Flashcards

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1
Q

What is interphase?

A

Growth and preparation for mitosis, this is during most of its lifetime

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2
Q

Description of growth 1?

A

Cell grows and carries out regular cell functions most of the time

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3
Q

Description of synthesis during interphase?

A

Duplication of DNA

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4
Q

Description of Growth 2?

A

Growth and preparation for cell division

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5
Q

Describe prophase in mitosis

A

Centrioles move to opposite poles, chromosomes become visible (coil up and thicken)

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6
Q

Description of metaphase

A

Centrioles form spindle fibres which push the chromosomes to line up in the middle of the cell

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7
Q

Description of anaphase

A

Spindle fibres pull the chromosomes towards poles, centromere splits, each new cell receives one chromatid from each chromosome

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8
Q

Description of telophase

A

Chromatids reach poles and nuclear envelope reforms, chromatids begin to uncoil and become less distinct

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9
Q

Describe mitosis

A

Reproduction of cells asexually in eukaryotes, creates two daughter cells

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10
Q

Describe cytokinesis

A

Cytoplasmic division (cytoplasm dividing), simultaneous to telophase

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11
Q

What stage of the cell cycle does duplication of DNA occur?

A

Synthesis

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12
Q

What are the two stages of cell cycle where growth and preparation of mitosis occurs?

A

Growth 1 and Growth 2

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13
Q

What stage of mitosis do the centrioles move to opposite poles?

A

Prophase

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14
Q

What stage of mitosis do the chromosomes line up in the middle?

A

Metaphase

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15
Q

What phase of mitosis does the spindle fibres attach to the chromosomes?

A

Anaphase

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16
Q

What phase of mitosis does the centromere split?

A

Anaphase

17
Q

What phase of mitosis do the chromatids reach poles occur?

A

Telophase

18
Q

What is the order of steps for mitosis?

A

Prophase, Metaphase, Anaphase, Telophase

19
Q

What is the purpose of the Growth 1 checkpoint in the cell cycle?

A

To check for DNA damage, nutrients sufficiency, cell size and growth patterns

20
Q

What can go wrong if the Growth 1 checkpoint of the cell cycle fails?

A

The cell cycle will stop while DNA damage is repaired or nutrients are imported

21
Q

What is the purpose of the Growth 2 checkpoint of the cell cycle?

A

To check for DNA damage and to make sure the cell size is big enough for division

22
Q

What is the purpose of the mitosis cell cycle check point?

A

To check the spindles for chromosome attachment defects in between metaphase and anaphase

23
Q

What can go wrong if the Growth 2 checkpoint of the cell cycle fails?

A

Cancer or tumors

24
Q

What can go wrong if the mitosis checkpoint of the cell cycle fails?

A

Non-disjunction, which results in aneuploidy cells

25
Q

What is the cell cycle?

A

The sequence of events that takes place from one cell division to another

26
Q

What is the G0 phase?

A

Cells don’t undergo division and stay the same, specialised cells like nerve cells

27
Q

What do centrioles do during mitosis?

A

They combine with another centriole to make a centrosome. The centrosome is where the spindles extend to attach to a chromosome

28
Q

What is apoptosis?

A

Programmed cell death

29
Q

What happens if a cell refuses to undergo apoptosis?

A

It will create a tumour that your body can not tell to die

30
Q

Why is apoptosis good?

A

It prevents the body from having too many cells, and allows the body to develop properly as a fetus