Cell Adaptation Flashcards

1
Q

Hyperplasia

A

Increase in the number of cells of an organ

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2
Q

MDx

A

Fibrous hyperplasia

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3
Q

Adaptation Response:

A

Atrophy

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4
Q

Metaplasia is reversible only if

A

Metaplasia is reversible only if the cause is removed

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5
Q

Adaptation Response

A

Hyperplasia

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6
Q

Hyperplasia occurs in cells that are capable of ____________.

A

Hyperplasia occurs in cells that are capable of replication.

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7
Q

Adaptation Response

A

Hyperplasia

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8
Q

Concentric Hypertrophy

A

growth of a hollow organ without overall enlargement, in which the walls of the organ are thickened and its capacity or volume is diminished.

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9
Q

2 MDx

A

Kidney - hydronephritis with secondary severe diffuse cortical atrophy

Ureter - hydroureter

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10
Q

T/F: When cells go through adaptation they preserve viability and function, its a reversible change.

A

True

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11
Q

Hypertrophic cardiomyopathy (HCM) is common in ____________.

A

Hypertrophic cardiomyopathy (HCM) is common in Main Coon Cats.

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12
Q

Metaplasia occurs most commonly in ___________ cells.

A

Metaplasia occurs most commonly in epithelial cells.

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13
Q

Hyperplasia may occur concomitantly with __________.

A

Hyperplasia may occur concomitantly with Hypertrophy.

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14
Q

Hypertrophic cardiomyopthy (HCM) in cats is due to a mutation in the____________.

A

Hypertrophic cardiomyopthy (HCM) in cats is due to a mutation in the MYBPC3 gene.

__________________________

Inherited autosomal dominant

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15
Q

Hypertrophy

A

Increased size of cells and thier functions

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16
Q

Adaptation Response:

(Normal = Right)

A

Atrophy

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17
Q

Hyperplasia is most commonly caused by

A

Hyperplasia is most commonly caused by excessive hormonal or growth factor stimulation

18
Q

MDx

A

Liver- hepatocellular carcinoma with nodular hyperplasia

19
Q

Metaplasia occurs in response to

A

Metaplasia occurs in response to chronic irritation

20
Q

Hypertrophy occurs due to

A

Hypertrophy occurs due to synthesis of more organelles and structural proteins

21
Q

Adaptation Response

(Normal = Left)

22
Q

Dysplasia occurs most commonly in _________ cells.

A

Dysplasia occurs most commonly in epithelial cells.

23
Q

MDx

A

Stomach- gastric lymphoid hyperplasia, multifocal

24
Q

Causes of atrophy

A

Decreased workload

Denervation

Decreased blood supply or oxygen

Inadequate nutrition

Loss of endocrine stimulation

Aging

25
Metaplasia may result in
Decreased function Increased propensity for malignant transformation
26
Principal responses of adaptation
Atrophy Hypertrophy Hyperplasia Metaplasia Dysplasia
27
MDx
Stomach - diffuse marked chronic gastric hypertrophy
28
Disease
Squamous Cell Carcinoma
29
Atrophy
Decrease in size and or number of the cells and their metabolic activity after normal growth has been reached
30
Metaplasia
Change in phenotype of a differentiated cell
31
Dysplasia
Abnormal development
32
Adaptation Response
Atrophy \_\_\_\_\_\_\_\_\_\_\_\_\_\_ Laryngeal Atrophy
33
Eccentric Hypertrophy
Hypertrophic growth of the walls of a hollow organ, especially the heart, in which the overall size and volume are enlarged.
34
Dysplasia is most commonly used in ___________ processes.
Dysplasia is most commonly used in **neoplastic** processes. \_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_ Carcinoma in situ
35
Etiology
Cryptosoridium serpentits
36
MDx
Kidney - nephrolith with hydronephrosis, cortical and medullary atrophy and medullary fibrosis, diffuse
37
Adaptation Response
Hypertrophy
38
Homeostasis
Tendency to stability in the normal body states of the organism; it is the ability to maintain internal equilibrium by adjusting its physiological processes
39
Atrophy occurs due to
Decreased protein synthesis and increased protein degradation in cells
40
Cell adaptation occurs when
Cell adaptation occurs when **the cell homeostasis is distorted by stresses or pathologic stimuli**