CC1 - TEST FOR CONJUGATION AND EXCRETION FUNCTION Flashcards

1
Q

End product of hemoglobin metabolism
Principal pigm ent in bile

A

Bilirubin

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2
Q

Also formed from destruction of heme containing proteins such as myoglobin, catalase, and cytochromeoxidase

 Are conjugated and excreted through the liver.

A

Bilirubin

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3
Q

Where does 85% of Bilirubin came from

A

heme of hemoglobin

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4
Q

Bilirubin 1

A
  • Unconjugated bilirubin
  • Water insoluble
  • Nonpolar bilirubin
  • Indirect bilirubin
  • Hemobilirubin
  • Slow reacting
  • Prehepatic bilirubin
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5
Q

Bilirubin 2

A
  • Conjugated bilirubin
  • Water soluble
  • Polar bilirubin
  • Direct bilirubin
  • Cholebilirubin
  • One minute prompt bilirubin
  • Post hepatic/ hepatic /obstructive/ regurgitative
    bilirubin
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6
Q

If bilirubin synthesis > liver clearance rate =

A

increased bilirubin level

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7
Q

Plasma concentration of bilirubin increases upon birth and reaches its peak on

A

the 5th day

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8
Q

Conjugated bilirubin RV

A

0-0.2 mg/dL (0 3 umol/L)

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9
Q

Unconjugated bilirubin RV

A

0.2-0. 8 mg/dL (3-14 umol/L)

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10
Q

Total Bilirubin RV

A

0.2-1.0 mg /d L (3-17 umol/L)

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11
Q
  • Conjugated bilirubin bound to albumin.
  • They have longer half life
  • It is formed due to prolonged elevation of conjugated bilirubin.
  • This is an abnormal albumin.
  • Helps in monitoring the decline of serum bilirubin
    following cholecystectomy.
  • It reacts with diazo reagent.
A

Delta Bilirubin

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12
Q

Delta Bilirubin RV

A

<0.2 mg/dL

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13
Q

DB formula

A

For DB = TB DB+ IB should not be performed in
neonatal patients for less than or equal to 14 day s.

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