(17) GGT - LIVER ENZYMES Flashcards
1
Q
Action: Catalyze the transfer of the γ-glutamyl residue from γ-glutamyl peptides to amino acids, H20, etc.
A
GGT ( gamma-glutamyl transferase )
2
Q
Most common donor γ-glutamyl peptide
A
glutathione
3
Q
NOTE:
Diagnostic significance of GGT
A
o dx of hepatobiliary disorders & chronic alcoholism
o sensitive marker for ethanol intoxication
o marker for occult alcoholism
4
Q
o Szaz Assay
▪ Absorbance of p-Nitroaniline is measured @ 405-420nm
* Product has color:
A
Assay for Enzyme Activity for GGT