case 5 Flashcards
what is a downstream approach to health?
treating what happens to the patients (as opposed to preventative). what most doctors do.
what is illness behaviour?
how people behave wen they have illness-an important part before they see the doctor.
when did zola make his triggers?
1973
what does the TCA cycle stand for?
tricarboxylic acid cycle
what can happen to the intermediates of the krebs cycle/
some of them when needed can be taken out and used for other reactions inside the cell.
in general, what happens in the krebs cycle?
energy from oxidation reactions is being generated and being stored in these electron carriers.
for each glucose/fructose, how many acetyl coAs are going into the Krebs cycle?
2
why is fat our main energy store?
because it has the highest calorific value.
what is TAG in terms of fat stores?
triacylglyceride. same as triglyceride. (or TG or triacylglycerol.) is an ester of glycerol and three fatty acids. the main constituents of body fat in humans.
why do you have a negative nitrogen balance in starvation?
you’re breaking down tissue protein for energy.
what are a-ketoacids?
acidic compounds that have a keto group adjacent to the carboxylic group in their structure. eg: amino acids without the amino group.
what is ketogenesis?
making ketone bodies
what are chylomicrons?
transport vesicles which transport fats around the body.
what is VLDL?
very low density lipoprotein (lol)
what happens in beta oxidation?
fatty acid molecules are broken down to generate acetyl-CoA, which enters the citric acid cycle, and NADH and FADH₂, which are co-enzymes used in the electron transport chain.
what type of fatty acid is palmitic acid?
long chained fatty acid
what is the main product of fatty acid synthesis?
palmitic acid-16C
what is a mimetic?
mimics a drug
what is the most commonly inherited defect of fatty acid oxidation?
MCADD (medium chain acyl-coA dehydrogenase deficiency)
what is the inheritance of MCADD?
autosomal recessive
what are the symptoms of babies with MCADD?
poor feeding drowsiness sleepiness vomiting low energy seizures (fits)
what are some potential causes of airway obstruction?
- drowsy/unconscious patients for whom the tongue can fall backwards
- vomit
- secretions
- tissue swelling
- laryngeal oedema
what is central cyanosis?
generalized bluish discoloration of the body and the visible mucous membranes.
what is the CRP test?
C-reactive protein test-blood test that levels measures of inflammation.