CardioVascular Physiology 3 Flashcards
Systole Defenition
contraction
Distole Defenition
Relaxation
Mechanical Events
- Late Diastole
- Atrial Systole
- Isovolumic Ventricular Contraction
- Ventricular Ejection
- Isovolumic Ventricular Relaxation
Late Diastole
- all chambers are relaxed, ventricles fill passively
- SL valves closed, AV valves open
- ventricle volume increases
- ventricle pressure low
Atrial Systole
- atrial contraction forces a small amount of blood into ventricles (15%)
- ventricle pressure increases
- ventricle volume increases
Isovolumic Ventricular Contraction
- increasing ventricle pressure
- pushes AV valves closed
- pressure not great enough to open SL valves
Ventricular Ejection
- ventricle pressure great enough to open SL valves
- ventricle volume begins decreasing
Isovolumic Ventricular Relaxation
- ventricle pressure decreases
- ventricle volume decreases
- blood flows back to close SL valves
Stroke Volume
is the amount of blood pumped by one ventricle during contraction
SV = EDV - ESV
- average is 70mL/beat
Cardiac Output
is the volume of blood pumped by one ventricle in a given period of time
CO = HR x SV
- average is 5L/min
Heart Murmur Timing
at the beginning and end of ventricle systole
Chronotropic effect
modulation of heart rate
- occurs on the SA Node, can be from psns or sns
Inotropic Effect
modulation of ventricular myocytes contractility
- only caused by sns
ANS heart rate receptors
Sympathetic: NE on beta1 receptors
Parasympathetic: ACh on M2 receptors
Modulation of Stroke Volume
stroke volume = contraction force
- contraction force is determined by the length of sarcomeres and the comtractility of the muscle