Cardiovascular Disease Flashcards

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1
Q

How do atheromas form

A

Damage to artery endothelium
By high blood p, white blood cells or lipids clumping to form fatty streaks
Build up of these abs connective tissues harden to form the fibrous plaque

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2
Q

Why are atheromas bad

A

Partially blocks lumen of artery
Restricts blood flow
Increase blood p

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3
Q

What is coronary heart disease

A

Coronary arteries contain lots of atheromas

Restricting blood flow to the heart

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4
Q

What is the scientific word for heart attack

A

Myocardial infarction

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5
Q

What diseases can atheromas cause

A

Myocardial infarction
Aneurysm
Thrombosis

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6
Q

What is an aneurysm

A

Blood travels through weakened artery at high blood p
Pushing inner layers of the artery (eg. The muscle layer) through the outer elastic layer
Forming all on like swelling

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7
Q

What happens when an aneurysm bursts

A

Haemorrhage

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8
Q

How is thrombosis formed

A

Atheroma ruptures the endothelium of the artery
Damages artery wall
Leaves rough surface
Platelets and fibrin accumulate at rough surface
Form blood clot
Blocking artery

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9
Q

What is a simple definition of thrombosis

A

Blood clot

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10
Q

Why is thrombosis bad

A

Block artery

Debris from rupture can cause a blood clot elsewhere

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11
Q

What cause myocardial infarction

A

Interrupted blood flow to the heart eg. By atheroma or thrombosis
Heart muscle doesn’t receive oxygen for respiration

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12
Q

Symptoms of myocardial infarction

A

Chest pain
Shortness of breath
Death

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13
Q

What are 3 risk factors to cardiovascular disease

A

Poor diet
Smoking
High blood p

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14
Q

Why does poor diet increase risk of CD

A

Increase blood cholesterol
One of the main constituents in fatty deposits of atheromas
Increase in Salt = increases blood p = aneurysm and thrombosis

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15
Q

Why does smoking Increase chance of cd

A

Contains nicotine ans CO
Nicotine = increase blood p
CO = reduces amount Of oxygen in blood = myocardial infarction
Reduces amount of antioxidants = less protection against cell damage = atheroma

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16
Q

How does high blood p increase risk of cd

A

Increase damage to artery walls
Atheroma formation
Blood clots = myocardial infarction

17
Q

What is an example of a genetic predisposition to cd

A

Diabetes