Cardiovascular Development 2 Flashcards

1
Q

Explain results of first breath

A

Expansion of lungs

Increased blood moving through pulmonary arteries

Release of inflammatory mediators

Release of Bradykinin

Increase O2

Decrease in prostoglandins (maternal origin)

All of this stimulates the wall of the ductus arteriosus to close

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2
Q

What leads to patent ductus arteriosus?

A

Ductus doesnt close, some sort of defect of receptors

Hypoxia at birth can also lead to this

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3
Q

When does bilateral tube formation occur?

A

When embryo begins to fold

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4
Q

What fuse to form a single primitive heart tube?

A

Two Endocardial tubes

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5
Q

What does the bulbis cordis form?

A

Most of the right ventricle and parts of the outflow tracts for the aorta and pulmonary trunk

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6
Q

What does the primitive ventricle form?

A

Most of the left ventricle

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7
Q

What does the primitive atrium form?

A

Anterior parts of the right and left atria

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8
Q

What do the sinus venosus form?

A

Forms the superior vena cava and part of the right atrium

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9
Q

Which direction does the bulbis cordis move?

A

Inferiorly, anteriorly and the embryos right

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10
Q

Which direction does the primitive ventricle move?

A

Moves to the embryos left side

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11
Q

Which direction does the primitive atrium and sinus venosus move?

A

Superiorly and posteriorly

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12
Q

Truncus Arteriosus

A

Output region of the heart

Develops into aorta and pulmonary trunk

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13
Q

Bulbus Cordis

A

A bulb-shaped region will become part of the right ventricle

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14
Q

Ventricle

A

Destined to become left ventricle

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15
Q

Atrium

A

A region that will expand to become both right and left atria

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16
Q

Sinus venosus

A

A paired region into which vena cava drain. The left sinus venosus becomes the coronary sinus and the right is incorporated into the wall of the right atrium

17
Q

What do endocardial cushions give rise to?

A

Heart valves and are critical for proper development of 4 chambered heart

18
Q

What forms endocardial cushions?

A

Cardiac jelly which is secreted by myocardium