cardiovascular 2 Flashcards
What is the leading cause for heart transplant
Cardiomyopathy
A group of heart muscle diseases that affect the structure & function of the myocardium
Cardiomyopathy
Most common type of cardiomyopathy
Dilated (congestive)
Increase chamber size
Decrease wall thickness
Occurs after infectious myocarditis; possible autoimmune process
Dilated cardiomyopathy
Inflammation & rapid degeneration of myocardial fibers decreased Contractility function & ventricular dilation
Dilated cardiomyopathy
Nitrates
Vasodilation
Decrease preload & after load
Loop diuretic
Helps with preload
ACE inhibitor
Vasodilator
Stops angiotensin I
Beta blockers
Decrease HR, B/P, CO
Anticoagulant
Risk for blood clots
Indotropic
Decrease HR
Most common cause of sudden death in otherwise healthy young people
Hypertrophic cardiomyopathy
Massive ventricular hypertrophy
Rapid forceful LV contraction
Impaired relaxation of ventricles
Enlarged ventricle septum
Hypertrophic cardiomyopathy
Most common symptom of hypertrophic cardiomyopathy
Exertional dyspnea
Primary diagnostic tool for hypertrophic cardiomyopathy
Echocardiogram
Resection/remove left ventricle, may remove septum tissue
Ventriculomyotomy
Inject alcohol into LA to give infarction to septal wall
Percutaneous transluminal septal myocardial ablation
What is the least common form of cardiomyopathy
Restrictive cardiomyopathy
Myocardial fibrosis, hypertrophy & infiltration
Restrictive cardiomyopathy
Maximum time from harvest to transplant
4 hours
What is the primary complication of heart transplant
Infection
Infection or inflammatory process of inner layer of heart and heart valves
Classified by cause or affected site
Infective endocarditis
Infective carditis that occurs in existing disased valves, sicker longer
Subacute
Infective endocarditis that affects healthy valves, rapidly progresses
Acute endocarditis
Symptoms of endocarditis
Low grade fever Chills Weakness New or changing murmur Affects multiple organ system
Linear streak under fingers
Red then brown/black
.
Oslers nodes
Tender, painful, size of pea, red/purple color on fingers
Janeways lesion
Sole of feet, flat painless, initially red then brown
How much fluid is in the pericardial sac?
10-15 ml
Late pericarditis
4-6 weeks after MI
Dressler syndrome
Rapid or slow fluid accumulation in pericardial sac
Pericardial effusion
Life threatening fluid accumulation in pericardium
Cardiac tamponade
What is a major sign of cardiac tamponade
Beck’s triad
Beck’s triad
Muffled heart sounds
Hypotension
JVD
Exaggerated drop in systolic arterial blood pressure upon inspiration
Pulsus paradoxus
Fluid aspirated from pericardial sac
Pericardiocentesis
infection/inflammation of pericardial sac
fibrous scarring thickened & adherent pericardium
chronic constrictive pericarditis
what mimics heart failure
chronic constrictive pericarditis
what confirms the diagnosis of chronic constrictive pericarditis
color doppler imaging
removal of pericardium
pericardectomy
inflammatory/infection disease of myocardium, orgainism invades myocytes with cell damage & necrosis
myocarditis
what confirms the diagnosis of myocarditis
endomyocardial biopsy
what do heart valves do
control unidirectional blood flow
the tricuspid and mitral valves are open during
diastole
the semilunar valves are open during
systole
what stabilizes the heart valves
chordae tendineae
“heart strings”
defined according to valve affected & type of altered function
valvular heart disease
valve orifice small, narrow
stenosis
incomplete closure of valve leaflets resulting in backward flow of blood
regurgitation
what is the most common valvular heart disorder
aortic stenosis & mitral regurgitation (left side of heart)
damage & scarring to valve leaflets & chordae tendineae, valves become thick, funnel shape, shortened (fish mouth)
mitral valve stenosis
common causes of mitral valve regurgitiation
MI, rhumatic heart disease
blood backflow from LV to LA
mitral valve regurgitation
therady pulses with cool, clammy extremities, shock and pulmonary edema are symptoms of
acute mitral valve regurgitation
what is the most common valvular heart disease in US
mitral valve prolapse
abnormal valve strucutre causing valve leaflets to buckle into LA in systole
mitral valve prolapse
blood flow is obstructed from LV to aorta
aortic valve stenosis
triad of symptoms for aortic valve stenosis
angina pectoris
syncope
exertional dyspnea
allows blood to flow back from aorta to LV
aortic valve regurgitation
results in increased blood volume in RA & RV
tricuspid and pulmonic valve disease
strong quick beat then collapses immediatly
water hammer pulse
what is used to diagnose valvular disorders
Echo/TEE
splits open fused leaflets, a balloon tipped catheter threaded from femoral artery/vein to stenotic valve, the balloon inflates to separate valve leaflets
precutaneous transluminal balloon valvuoplasty
what is needed after a mechanical heart valve
long term anticoagulants
what is the INR therapeutic range for a mechanical valve
2.5-3.5