Cardiovascular Flashcards
The only fluid tissue in the body
Blood
Specialized connective tissue in which living blood cells, called the
Formed elements
suspended in a nonliving fluid matrix called
Plasma
Total blood volume in an average adult is about ___ in females and ___ in males
4-5
5-6
Blood makes up __ of the total weight of the body.
8%
Blood components
- Withdraw blood and place in tube
- Centrifuge the blood sample
- Plasma, buffy coat and erythrocytes
55% of the whole blood
Plasma
Least dense component
Plasma
Leukocytes and platelets
Buffy coat
<1% of whole blood
Buffy coat
45% of whole blood (hematocrit)
Erythrocytes
Most dense component
Erythrocytes
Formed elements
Buffy coat and erythrocytes
Blood – Physical Characteristics
• Sticky, opaque fluid with a metallic taste
• Color varies from scarlet to dark red.
• Blood is denser than water and about five times
more viscous, largely because of the formed
elements.
• Slightly alkaline (pH – 7.35-7.45)
Functions of blood
Protection
Distribution
Regulation
A pale - yellow fluid
Plasma
Plasma consists of about:
• 91% water
• 7% proteins
• 2% other solutes
Plasma proteins include the following:
• Albumin 58%
• Globulin 38%
• Fibrinogen 4%
Contributes to osmotic
pressure
Albumin
Composed of gamma,
alpha and beta
Globulin
Contributes to blood
clot
Fibrinogen
The process of blood cell production
Hematopoiesis
All the formed elements of the blood are derived
from a single population of cells called
Stem cells
Formed elements composed of the following:
• 95% of red blood cells (erythrocytes)
• 5% of white blood cells (leukocytes) and blood platelets
(thrombocytes)
Biconcave disk, no
nucleus, contains
hemoglobin which colors
the cell red.
Red blood cells (erythrocytes)
6.5-8.5 micrometer in
diameter.
Red Blood Cells (Erythrocytes)
A microliter of blood
contains 5 million of red
blood cells.
Red blood cells (erythrocytes)
Function: Transports
oxygen and carbon dioxide
Red blood cells (erythrocytes)
Spherical cells with a
nucleus
White Blood Cells (Leukocytes)
Body’s defense against
pathogens
White blood cells (leukocytes)
A microliter of blood
contains 5000-10,000
white blood cells.
White blood cells (leukocytes)
White blood cells composed of five types
• Neutrophil 60-70%
• Basophil 0.5-1%
• Eosinophil 2-4%
• Lymphocyte 20-25%
• Monocyte 3-8%
Granulocytes
Neutrophil
Bashil
Eosinophil
Agranulocytes
Lymphocyte
Monocyte
Minute fragments of cells, each consisting of
small amount of cytoplasm surrounded
by cell membrane.
Platelets (thrombocytes)
A microliter of blood
contains 150,000-
400,000 platelets.
Platelets (thrombocytes)
Function: Preventing Blood loss
Platelets (thrombocytes)
A laboratory examination of blood yields
information that can be used to evaluate a person’s
health. This involves CBC, Differential white blood
cell count, platelet count, prothrombin time, etc.
Diagnostic blood test
Analysis of blood that provides much useful
information
Complete blood count
Determines the percentage of each of the five kinds
of white blood cells.
Differential White Blood Cell
The blood’s ability to clot can be assess through:
Platelet count
Prothrombin time measurement
calculates how long it takes for the blood to start clotting. Normally – 9-12 seconds.
Prothrombin Time Measurement
Normal value: 150, 000 – 400, 000 platelets per microliter of blood.
Platelet count
shaped like a blunt cone and
approximately the size of a closed fist and has a
mass of 250-350g.
adult heart
Located in the thoracic cavity between two pleural
cavities that surround the lungs.
Heart
midline partition
Mediastinum
cavity of the heart
Pericardial cavity
Pump blood throughout the bod
Heart
Beats approx. 100,000 times daily carrying 8000L of
blood.
Heart
Covering of the Heart
Pericardium
A sac consisting of
fibrous and serous
pericardia.
Pericardium
Two layers of pericardium
• Fibrous Pericardium
• Serous Pericardium
- parietal & visceral
Histology of the heart
Heart wall
3 layers of heart wall
Epicardium
Myocardium
Endocardium
Outermost layer of the heart
Epicardium
Composed of simple squamous epithelium and an areolar connective tissue (deep area)
Middle layer of the heart wall
Myocardium
Composed of cardiac muscle tissue.
Myocardium
Responsible for the overall contraction of heart necessary to pump blood
Myocardium
• Innermost layer of the heart
• Composed of simple squamous epithelium and an areolar
Endocardium
4 chambers pf the heart
Superior Atria 2
Inferior Ventricles 2
receives the blood from the vein
Superior Atria (2)
pump blood away from the heart from the atria
Inferior Ventricles (2)
Internal Partitions of the heart
Interatrial Septum
intraventricular septum
separates the atrial chambers
Interatrial Septum
separates the ventricular chambers
Interventricular Septum
Grooves on the heart surface:
Coronary sulcus
Anterior Interventicular sulcus
Posterior interventicular sulcus
separate the atria from the ventricles
Coronary sulcus
from coronary sulcus to anterior surface of the heart
Anterior Interventricular Sulcus
from coronary sulcus to posterior surface of the heart
Posterior Interventricular Sulcus
Veins that carry blood to the heart:
- Superior Vena Cava
- Inferior Vena Cava
- Coronary Sinus
- Four Pulmonary Veins
Arteries that carry blood away from the heart:
- Pulmonary Trunk
- Aorta
- Pulmonary Arteries
VanPutt
Located between the right atrium and the right
ventricle(tricuspid valve) and between the left atrium
and left ventricle (bicuspid/mitral valve).
Atrioventricular Valves (AV Valves)
the right atrium and the right ventricle
tricuspid valve
he left atrium and left ventricle
bicuspid/mitral valve
Prevent backflow into the atria
Antrioventricular valves
Each ventricle of anteioventicular valves contains cone-shaped, muscular pillars
called
papillary muscles
Atrioventricular valves attached to a connective tissue strings called
chordae tendineae.
The aorta and pulmonary trunk possess
aortic and
pulmonary semilunar valves.