Cardiology Flashcards
Angina first line management
Beta blocker/ccb
Angina management
- Aspirin, statin, s/l GTN to abort angina attacks.
- Beta-blocker or CCB.
If CCB used as monotherapy, a rate-limiting one such as verapamil or diltiazem should be used.
If used in combination with a beta-blocker then use a longer-acting dihydropyridine calcium channel blocker (e.g. amlodipine, modified-release nifedipine) - Titrate medications to max tolerated doses.
- If still symptomatic after monotherapy with a beta-blocker add a calcium channel blocker and vice versa.
- If can’t do step 4 then add one of:
a long-acting nitrate
ivabradine
nicorandil
ranolazine
What can’t you prescribe with a beta blocker
Verapamil (risk of complete heart block)
What is used to treat torsades
IV magnesium
Becks triad
For tamponade
Muffled HS
Raised JVP
Low bp
How to screen for ADPCKD
USS
Hypokalaemia ECG changes?
PR prolongation and flattened T waves
When could you cardiovert for AF
If within 48h.
If not need to anticoagulate and wait 3 weeks.
How is familial hypercholesterolaemia treated in pregnancy?
colesevalm. (Bile salt thing)
Only thing thats safe in pregnancy/ breastfeeding.
What criteria is used to diagnose familial hypercholesterolaemia?
Simon Broome.
What would make you suspect familial hypercholesterolaemia
TC > 7.5 mmol/L
+/-
A personal or family history of premature coronary heart disease (event u 60).
How to clinically diagnose familial hypercholesterolaemia
Use Simon Broome criteria:
In adults total cholesterol > 7.5 and LDL > 4.5
plus:
for definite FH: tendon xanthoma in patients or 1st or 2nd degree relatives or DNA-based evidence of FH
for possible FH: family history of myocardial infarction below age 50 years in 2nd degree relative, below age 60 in 1st degree relative, or a family history of raised cholesterol levels
What are you looking for when assessing response to statin in familial Hypercholesterolaemia?
aim to achieve at least a 50% reduction in LDL
How would you treat familial hypercholesterolaemia?
Atorva 20 or rosuva 10.
Atorva 20 if renal impairment.
Hypercalcaemia ecg changes
Shortened QT
Osborn (J) waves if severe.