Carcinoma cervix 2B

Question 1

risk factors

Answer 1

early sexual activity at a young age and ↑no. of sexual partners

Question 2

what is the main causative agents

Answer 2

• HPV is main causative agent (serotype 16 &18)

Question 3

what is the most common cell type

Answer 3

squamous cell carcinoma and then adenocarcinoma

Question 4

what has been linked with adenocarcinoma

Answer 4

exposure to DES has been linked

Question 5

classic presentation

Answer 5

 Postcoital bleeding
 Abnormal vaginal bleeding, watery vagina discharge and pelvic pain
 Bimanual examination = Palpable mass within the cervix

Question 6

diagnosis

Answer 6

Pap smear and primary prevention programs (ie.e evey 3 years >25 and every 5yrs >45yrs )

Question 7

patient with abnormal smear

Answer 7

should be sent to tertiary centre for cervical biopsy via colposcopy

Question 8

treatment

Answer 8

 Cone biopsy if patient wishes for fertility
 In invasive cervical carcinmona (contained within the cervix, uterine corpus and vagina) = radical hysterectomy
 Cisplatin based chemotherapy