Cancer

Question 1

CA125

Answer 1

Ovarian ca

Question 2

CA 19-9

Answer 2

Pancreatic

Question 3

CA 15-3

Answer 3

Breast cancer

Question 4

AFP

Answer 4

HCC, Teratoma

Question 5

CEA

Answer 5

CRC

Question 6

psa

Answer 6

prostate

Question 7

S-100 tumour marker

Answer 7

melanoma, schwannoma

Question 8

Bombesin tumour marker

Answer 8

SCLC Gastric Ca, neuro-blastoma

Question 9

Cervical ca hPV strains

Answer 9

HPV 16,18,33

Question 10

Chemo N&V meds

Answer 10

Low risk then metoclopramide. High risk odansetron (5=HT3 antagonist)

Question 11

Lynch syndrome - inheritance + what it means

Answer 11

AD, CRC + endometrial at young age

Question 12

Li fraumeni syndrome

Answer 12

Ab to P53 (TSG), germline mutation
↑ incidence sarcomas/leukaemias
BRCA1+2. Breast + ovarian ca. In men prostate cancer

Question 13

Gardners syndrome

Answer 13

AD, FAP - colonic polyps

Question 14

Back pain (ma be worse on lying down/coughing), LL weakness/neuro + known malignancy

dxix,mx

Answer 14

Neoplastic spinal cord compression
Back pain (ma be worse on lying down/coughing, LL weakness/neuro
Urgent MRI<24hrs
High dose dex + assessment

Question 15

Emergency ass with lung cancer
Dyspnea, swelling, headache, visual disturbance, ↑ JVp (SCLC)
Might do endovascular stent for symptoms

diagnosis

Answer 15

SVC Obstruction

Question 16

Cisplatin s/e

Answer 16

decrease mg