C8.2 - Microbial Interference and Surface Virulence Flashcards
Type of Interference - Streptococci
Kill Phagocyte
Inhibit Chemotaxis
Resist phagocytosis
Resist digestion
Kill phagocyte (Streptococci)
Streptolysin induces lysosomal discharge into cell cytoplasm
Inhibit chemotaxis (Streptococci)
Streptolysin
Resist phagocytosis (Streptococci)
M substance
Type of Interference - Staphylocci
Kill phagocyte
Inhibit opsonization
Resist killing
Kill phagocyte (Staphylococci)
Leukocidin induces lysosomal discharge into cell cytoplasm
Inhibit opsonization (Staphylococci)
Protein A blocks Fc portion of Ab
Resist killing (Staphylococci)
Cell wall mucopeptide
Bacillus anthracis - Type of Interference
Kill phagocyte
Resist killing
Kill phagocyte (Bacillus anthracis)
Toxic complex
Resist Killing (Bacillus anthracis)
Capsular polyglutamic acid
Resist phagocytosis (unless Ab present) (Haemophilus influenzae)
Polysaccharide capsule
Resist phagocytosis (unless Ab present) - Pseudomonas aeruginosa
“Surface slime” (polysaccharide)
Klebsiella pneumoniae - Type of Interference
Resist Digestion