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Pharmacology > Bronchial Asthma > Flashcards

Bronchial Asthma Flashcards

1
Q

Anti-asthmatic drugs are

A

Bronchodilator
Anti inflammatory
Other effective drugs

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2
Q

Bronchodilators classification

A

B2 agonist
Xanthine derivatives
Anti muscarinic

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3
Q

B2 agonist selective

A

Salbutamol
Terbutalin
Salmetrol
Formetrol

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4
Q

Non selective

A

Adrenaline
Isoprenaline

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5
Q

Xanthine derivatives

A

Aminophylline
Theophylline
Doxophylline

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6
Q

Anti muscaranic

A

Ipratropium bromide
Tiotropium bromide

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7
Q

Anti inflammatory classification

A

Steroid
Mast cell stabiliser

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8
Q

Anti inflammatory classification

A

Steroid
Mast cell stabiliser

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9
Q

Oral steroid for asthma

A

Prednisolone

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10
Q

Oral steroid for asthma

A

Prednisolone

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11
Q

I/V anti asthmatic

A

Hydrocortisone

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12
Q

Inhaler steroid

A

Fruticasone
Trimcinolone
Beclomethasone
Betamethasone
Budesonide

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13
Q

Mast cell stabiliser

A

Sodium chromoglycate
Ketotifen

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14
Q

Other effective drugs

A

Montelukast
Zafirlukast
Roflumilast
Cilomilast

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15
Q

Indications of salbutamol

A

Br. Asthma
COPD
Sleep apnoea
As tocolytic agent

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16
Q

A/E of salbutamol

A

Palpitation
Tremor
Tachycardia
Arrhythmia
Nervousness
Restlessness
Insomnia
Hypokelemia

17
Q

Contraindication of salbutamol

A

IHD
Hyperthyroidism
Arrhythmia

18
Q

A/ E of aminophylline / theophylline

A

Headache
Dizziness
Vertigo
Palpitation
Tachycardia
Insomnia
Arrhythmia
Hypotension
Restlessness

19
Q

A/E of montelukast

A

headache
Rash
Eosinophilia
Neutrophilia
Eosinophilia with vasculitis

20
Q

A/E of montelukast

A

headache
Rash
Eosinophilia
Neutrophilia
Eosinophilia with vasculitis

21
Q

Role of inhaler steroid

A

Increase sensitivity of adrenaline to bronchial smooth muscle = bronchodilation
Inhibit Ag-Ab reaction = suppression of inflammatory response
Inhibit of LT , PG, PAF synthesis = decrease bronchial hyper activity
Decrease capillary permeability = decrease bronchial oedema and congestion

22
Q

Benefits of inhaler steroid

A

Directly acts in the site of action
Rapidly relief of bronchial asthma
Less dose requirement
Less a/e
More patient compliance

23
Q

Disadvantage of inhaler salbutamol

A

Dryness of airway
Irritation if airway
Oropharyngeal candidiasis
Knowledge needed
Expensive

24
Q

Roflumilast is

A

Selective phosphodiesterase -4 inhibitor

25
Q

Indication of Roflumilast

A

Maintainence and treatment of severe COPD
Bronchial asthma

26
Q

A/E

A

Diarrhoea
Nausea
Headache
Insomnia
Anxiety
Nervousness
Depression

27
Q

Contraindications

A

Hypersensitive to Roflumilast
Moderate to severe liver impairment
Pregnancy

Pharmacology (7 decks)

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