Brainstem Anatomy Flashcards
What is the function of the reticular formation?
maintenance of consciousness
What is the only cranial nerve not attached to the brainstem?
CN 1
What are the 3 important contents of the medulla?
Medulla:
Pyramids
Olives
Fourth Ventricle
What are the 4 important contents of the pons?
Pons:
- Basal Pons
- Middle Cerebellar
- Peduncle
- Part of 4th ventricle
What are the 4 important contents of the midbrain?
Midbrain:
Inferior/Superior Colliculi
Superior Cerebellar Peduncle
Cerebral Peduncle
Cerebral AQUEDUCT
What are the following associated with in the brainstem?
- Superior Cerebellar Peduncle (SCP)
- MCP
- ICP
- Midbrain
- Pons
- Medulla
What forms the following areas of the Posterior Fossa?
- Floor
- Roof
- Brain Divisions
- Floor = Occipital & Temporal Bone
- Roof = Tentorium
- Cerebellum & Brainstem
Where does CN 3 emerge from? What can crush it? What kind of gaze would it create
INTERPEDUNCULAR FOSSA
- Uncus
- Lateral gaze
What is the mesencephalon?
Midbrain
What is another term for the Cerebral peduncles? For the Inferior & Superior Colliculi?
- Crus Cerebri
- Corpora Quadrigemina OR
Tectum
Which colliculi are involved with hearing? Vision? Which use the medial & lateral geniculates coming from the Thalamus?
SLO AIM
Superior Colliculi uses the Lateral Geniculate for OPTIC functions (vision)
Inferior Colliculi uses MEDIAL Geniculate for Auditory function
Which cerebellar peduncles are afferent? Efferent?
Superior = EFFERENT (VSCT)
Middle & Inferior = Afferent
(inferior for DSCT &CCT)
Where are the cerebral peduncles located? What do they connect? What fibers do they contain?
Midbrain
- connect cerebrum with brainstem & SPINAL CORD
- MYLENATED fibers (white matter - appear black in stain)
What are the fibers call that are leaving the Olive of the medulla and traveling to the cerebellum?
Climbing fibers
Where do the CST fibers decussate? What kind of cells are in the CST?
- in the pyramidal tract of the MEDULLA
- Pyramidal cells (Betz cells)
Where is the tentorium located? What meningeal layer is it composed of?
POSTERIOR CRANIAL FOSSA
- DURA
What structures are lateral to the 3rd ventricle? What does the 4th ventricle look like?
THALAMUS
- diamond shaped
Where do the following nerves originate from
3, 4 , 5, 6, 7, 8, 9, 10, 11, 12
3 = Interpeduncular fossa 4 = DORSUM of brain (only one that crosses the brain as well) 5 = Basal Pons 6 = pontomedullary junction 7,8,9 = pontomedullary angle 10 = dorsal to OLIVE 12 = ventral to OLIVE(front)
11 = from cervical spinal cord on the side
What must be ripped off for us to see the 4th ventricle?
Cerebellum
Which gland (pituitary/pineal) is ventral? Dorsal?
Pituitary = ventral
pineal = dorsal
Where does the pineal gland project?
Dorsally by the 3rd ventricle
What is located near the thalamus and concerned with vision?
PULVINAR
What is the function of mamillary bodies? How are they connected to the hippocampus? Are they found ventrally or dorsally?
MEMORY
- connected via FORNIX
- degenerate with alcoholism*
VENTRAL
What are the 6 major structures found in a cross section of the CAUDAL MEDULLA (low)?
- Pyramids
- Internal Arcuate Fibers (decussating in medulla)
- N. Gracilis
- N. Cuneatus
- Spinal tract & Nucleus of 5
- Medial Lemniscus
What vertebral levels are the following associated with:
- F. Gracilis
- F. Cuneatus
- Nucleus Dorsalis (Clark’s Nucleus)
- C8-L3
- C1- C7, T1-T6
- C8-L2
(F. Cuneatus takes over
What helps afferent fibers reach Clark’s Nucleus (Dorsalis) at the level of L3 & lower?
F. Gracilis (LEGS = low)
What helps us feel pain & sensation on the face?
Spinal Trigeminal Tract & Nucleus
- from PONS
Where does the spinal trigeminal tract descend from? What ganglion does it pass?
PONS
- down to cervical cord to synapse on Spinal Trigeminal nucleus
- SEMILUNAR GANGLION
What are the 4 major structures in the cross section of the ROSTRAL MEDULLA?
- Inferior Cerebellar Peduncle
- Inferior Olivary Nucleus
- Open 4th ventricle
- MLF
What is the function of MLF?
coordinates the nuclei of 3,4,6 with each other & spinal reflexes
What are the 5 major structures in the cross section of the CAUDAL Pons?
- Deep Cerebellar Nuclei
- Basal Pons
- Pontine Nuclei
- Ponto-cerebellar fibers (mossy)
- MIDDLE Cerebellar Peduncle
What are the 4 Deep Cerebellar Nuclei, (medial to lateral)
Fat Guys Eat Donuts
- Fastigal
- Globose
- Emboliform
- Dentate
What are the 4 major structures in the cross section of the ROSTRAL Pons?
- Basal pons
- beginning of PAG
- Medial Lemniscus preparing to enter thalamus
- STT entering VPL
- SCP prepares to cross
Where does the SCP prepare to cross? (enters) Where does it cross?
Rostral Pons
- Caudal Midbrain
What are the 4 major structures in the cross section of the CAUDAL MIDBRAIN?
- Crossing of SCP (VSCT)
- Inferior Colliculi
- Cerebral Peduncle
- TRUE AQUEDUCT
What tract runs in the center of the Crus Cerebri/ Cerebral Peduncle?
CST
What are the 4 major structures in the cross section of the ROSTRAL MIDBRAIN?
- Cerebral Peduncle
- CN 3
- SUbstantia Nigra
- Red Nucleus
(& superior Colliculi)
Degeneration of which part of the brain leads to Parkinsons? Which neurotransmitter is released in this area?
SUBSTANTIA NIGRA
- dopamine
What are the neurotransmitters associated with the following brainstem nuclei?
- Raphe
- Locus Cereleus
- Substantia Nigra & VTA
- Nucleus Basalis of Meynert & Septal Nuclei
- Seratonin
- Noradrenaline
- DOPAMINE
- Acetylcholine
Which neurotransmitter level is low in Alzheimer’s disease? Which nuclei does this originate from?
- Acetylcholine
2. Nucleus Basalis of Meyner & Septal Nuclei
Where does the Medial Lemniscus form?
Caudal medulla
Where is the inferior olivary nucleus & part of the 4th ventricle found?
ROSTRAL MEDULLA
Where is the middle cerebellar peduncle found?
Caudal Pons
Where is the red nucleus & substantia nigra found?
ROSTRAL MIDBRAIN
Where does the spinal trigeminal tract descend before it synapses on the spinal trigeminal nucleus?
from Pons to Cervical cord
What fibers make up the IAF? Which tract/pathway is associated with this?
F. CUneatus & F. Gracilis
- DCP - dorsal column pathway
What nucleus is equivalent to the Spinal Trigeminal N. of 5?
Nucleus Proprius of the STT (spinothalamic tract)
- associated with pain & sensation
Where does the Medial Lemniscus prepare to enter the Thalamus (which rostral/caudal level of brainstem)
ROSTRAL PONS
What is the periaqueductal grey responsible for?
Modulation of pain
What cells does the CST originate from?
PYRAMIDAL CELLS
What is responsible for the following:
- Control of Movement
- Modulates pain pathway
- Autonomic Reflex Circuitry
- Controls arousal and consciousness
RETICULAR FORMATION
What nucleus has extensive CNS projections and can adjust background level sensitivity? Where is it found n the brainstem?
LOCUS CERULEUS
- BLU DOT special
- found in the PONS
What are the white fibers that decussate in the Caudal Midbrain , in between lies the VTA?
Superior Cerebellar Peduncle
Which region is the raphe found? What levels may it adjust?
Caudal Pons
- levels of attention or arousal
What are 2 key nuclei in the basal forebrain? Where to they project?
- Basal N. of Meyner - CEREBRUM
2. Septal Nuclei - HIPPOCAMPUS
SE Raphe’s Substantial Dopey blue NE’s
Raphe—Serotonin Substantia Nigra—dopamine Locus Ceruleus (blue)—noradrenalin
Uncle Meynert has trouble remembering to move his cholinergics
Basal nucleus of Meynert contains cholinergic (ach) containing neurons which, when damaged, may cause the memory destroying disease called Alzheimer’s
Which arteries are responsible for Wallenburg Syndrome? Which arteries are they branches of?
SCA - Basilar
AICA - Basilar
PICA - Vertebral
Stroke of which part of the brain is the reason Wallenburg Syndrome developed?
Dorsal Lateral Medulla
Which artery of the Circle of Willis supplies the medial aspect of the brain? Lateral?
- Anterior Cerebral A.
2. Middle Cerebral A.
Which artery directly feeds the lower medulla?
PICA (off of vertebal A.)
- main artery responsible for Wallenburg
What are the symptoms of Lateral Medullary Syndrome of Wallenburg?
Balance, taste, speech, pain, Horner’s syndrome
- loss of pain/sensation on is face
- loss of pain/sensation on contralateral side of LOWER BODY
What is found below T6?
F. Gracilis
No cuneatus
Where does the Corticospinal Tract reside in the cervical spinal cord?
Lateral Funiculus
Where do the pyramids cross?
CAUDAL MEDULLA (lowest –> CST)
The lateral cuneate nucleus plays a role in which tract? What functions is this tract responsible for?
CCT
- unconscious proprioception
The cochlear nucleus are found on which peduncle?
Inferior Cerebellar Peduncle
The caudal pons has which CN nuclei?
6,7
Which brainstem level are the following located in:
- Red Nucleus
- Inferior Colliculi
- Nucleus Gracilis
- Inferior Olivary nucleus
- Decussation of Superior Cerebellar Peduncles
- Rostral Midbrain
- Caudal Midbrain
- Caudal Medulla
- Rostral Medulla
- Caudal Midbrain
Which artery supplies the following:
- Olive
- Basal Pons
- Middle Cerebellar Peduncle
- Inferior Cerebellar Peduncle
- Cerebral Peduncle
- PICA, vertebral
- Basilar A.
- AICA
- PICA
- Posterior Cerebral