Bone Tumours Flashcards
What are risk factors for primary bone tumours?
Previous radiotherapy, previous cancer, Paget’s disease, benign bone lesions
Where are primary bone tumours commonly found?
Long bones
Describe bone pain experienced in primary bone tumours?
Worse at night, constant or intermittent, resistant to analgesia, may increase in intensity
What MSK symptoms are present in bone tumours?
Bone pain, atypical bony or soft tissue swelling/masses, pathological fractures, mobility issues, inflammation and tenderness
What mobility issues might be present?
Unexplained limp, joint stiffness, reduced range of motion
What other symptoms might be present?
Easy bruising, systemic symptoms
What is the first line investigation?
X-ray
What is the gold standard investigation?
Biopsy
What blood tests would you do?
FBC, ESR, ALP, lactase dehydrogenase, calcium, U&E
Where would you CT?
Chest, abdomen, pelvis
How do you manage bone tumours?
Chemo and radiotherapy, surgery
What surgery options are available?
Limb sparing or amputation
What are the most common bone tumours?
Chondrosarcoma, osteosarcoma, Ewing sarcoma
What tumours commonly metastasise to bone?
Breast, lung, prostate, thyroid, kidney
