Bone and Joint infections Flashcards

1
Q

Bone Infection

A

Osteomyelitis (almost always bacterial)

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2
Q

what are the possible routes for osteomyelitis?

A

Haematogenous
Non-Haematogenous
direct inoculation, local invasion

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3
Q

where does the bone receives its major blood supply?

A

loop capillaries around the metaphysis

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4
Q

what is the area where most haematogenous spread goes to?

A

metaphysis

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5
Q

epiphysis can be infected if the shaft of the born is infected?

A

no because of the mineralisation of the metaphysis

(can only happen during childhood)

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6
Q

in children a condition can develop from osteomyelitis that does not happen in adulthood

A

Septic Arthritis

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7
Q

what is the main bacteria that causes osteomyelitis? where does it tend to come from?

A
Staphylococcus aureus (99%)
same bacteria can be isolated i the skin (82% of cases)
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8
Q

what is a possible causative agent of osteomyelitis after chicken pox infection?

A
Streptococcus pyogenes (GAS)
ß haemolysis
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9
Q

what is a possible causative agent of osteomyelitis in new borns and infants?

A

Haemophilus influenza type B (encapsulated)
other Gram-
Group B streptococci (S. agalactiae)
ß haemolysis

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10
Q

osteomyelitis is more prevalent in children than adults T/F

more prevalent in boys than girls T/F

A

T

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11
Q

what are the symptoms of osteomyelitis?

A

fever, painful limping, history of trauma (1/3 of cases)

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12
Q

what are the most common bones involved in osteomyelitis?

A

humerus

femur and tibia

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13
Q

diagnosis of osteomyelitis requires?

A

Blood culture not always good as the bacteria might have disappeared from the blood
WCC
however inflammatory markers give a clue
CRP, Erythrocyte Sedimentation Rate (ESR)
Xray

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14
Q

which one between CRP, Erythrocyte Sedimentation Rate (ESR) peaks faster and stays elevated for longer?

A

CRP protein within 24hrs

ESR lasts for longer

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15
Q

what is the best study undergone for the diagnosis of osteomyelitis?

A

Bone Scan
MRI
aspiration of the bone

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16
Q

if the bacteria isolated is coagulase positive?

A

staph aureus

17
Q

what is the empiric treatment osteomyelitis?

A

Flucloxacillin for S. aureus
Cephalosporins (for anything else)
if neonate use cefotaxime because it is better for Gram- causative agents
if complicated IV antibiotics for 3-5 days