Blood Type Origins

Question 0

Many genes that encode for the same phenotype

Answer 0

Polygeny

Question 1

Gene that has many alleles across a population

Answer 1

Polymorphism

Question 2

Phenomenon which activates the complement cascade

Answer 2

Binding of antibodies on antigens of foreign bodies

Question 3

System made up of distinct plasma proteins that react with one another to make pathogens susceptible to phagocytosis

Answer 3

Complement system

Question 4

Precursor for all ABO blood types

Answer 4

H antigen

Question 5

Locus of FUT1 gene encoding fucosyltransferase

Answer 5

Chromosome 19

Question 6

ABO locus

Answer 6

Chromosome 9

Question 7

Enzyme associated with A antigen

Answer 7

Alpha-1,3-N-acetylgalactosamine transferase

Question 8

Enzyme associated with B antigen

Answer 8

Alpha-1,3-galactosyl transferase

Question 9

Allele which lacks a guanine nucleotide at position 261 of exon 6

Answer 9

i (for type O)

Question 10

Site of attachment for ABO antigens

Answer 10

RBC membrane glycoproteins

Question 11

Persons who have ABO antigens in other body fluids except for CSF

Answer 11

Secretors

Question 12

Antigen associated with Rh blood typing

Answer 12

D antigen

Question 13

T/F: ABO antigens are glycoproteins whereas Rh antigens are proteins

Answer 13

True

Question 14

Protein which gives rise to D antigen

Answer 14

RHO protein

Question 15

Protein which gives rise to C/c and E/e antigens

Answer 15

RHCE protein

Question 16

Function of RHD and RHCE membrane multipass proteins

Answer 16

Transport of ammonium across RBC membrane

Question 17

Immune response of an immunocompetent individual to foreign antigens of the same species

Answer 17

Alloimmunization

Question 18

Treatment for erythroblastosis fetalis

Answer 18

RhoGAM

Question 19

Genes which encode for antigen proteins located on the surface of white blood cells

Answer 19

Human leukocyte antigens/major histocompatibility complexes

Specific to humans ang HLA

Question 20

MHC presented to cytotoxic T cell

Answer 20

MHC I

Question 21

MHC detected by helper T cells

Answer 21

MHC class II