Blood & Bone Marrow Flashcards

1
Q

What blood protein maintains oncotic pressure?

A

Albumin

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2
Q

What is the difference between serum and plasma

A

-Serum is liquid remaining after blood has clotted
-Plasma is liquid in unclotted blood

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3
Q

Where does hematopoiesis primarily occur?

A

Adult bone marrow

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4
Q

What species utilize the spleen as well as bone marrow for hematopoiesis?

A

Mouse, Ferret, hedgehog

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5
Q

Where is spongey bone located?

A

-Proximal ends of long bones
- Flat bones

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6
Q

What cell type give rise to all other blood cells?

A

Pluripotential stem cells

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7
Q

What is the term for RBC production? WBC? Platelets?

A

-Erythropoiesis
-Granulopoiesis
-Megakaryopoiesis

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8
Q

What two methods can you use to assess bone marrow?

A

-Aspirate
-Core biopsy

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9
Q

Which species RBC have nuclei?

A

Bird, Reptile, Amphibian

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10
Q

What is the most common (numerous) granulocyte? (WBC)

A

Neutrophils

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11
Q

What is the function(s) of neutrophils?

A

-First cell type found in any inflammatory reaction
-Essential for defense against bacterial infection

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12
Q

What are the main functions of eosinophils?

A

-Defense against parasites
-Regulation of allergic reactions

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13
Q

What is the function of basophils?

A

promote inflammation

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14
Q

How can you differentiate between mast cells and basophils?

A

-If it is blood, most likely basophil
-If it tissue, most likely mast cell
But make sure to look at nucleus if visible

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15
Q

What are the two agranulocytes?

A

Monocytes and lymphocytes

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16
Q

What is the role of lymphocytes?

A

-Important in protection against microbes and neoplasia

17
Q

What are the two types of lymphocytes and their roles?

A

-B lymphocytes: Production of antibodies
-T lymphocytes: Destruction of infected or neoplastic cells

18
Q

What is a plasma cell?

A

A reactive lymphocyte

19
Q

Is a platelet a cell?

A

No, it is a piece of megakeriocyte cytoplasm

20
Q

Where does lymphocyte production take place? what is the role of the bone marrow?

A

Mainly takes place in lymph nodes, however the bone marrow provides precursors

21
Q

What is an immature RBC called?

A

Reticulocytes

22
Q

What are the 3 granulocytes?

A

Neutrophils, eosinophils, basophils

23
Q

What is the difference between monocytes and macrophages?

A

The cell is called a monocyte in the blood, but a macrophage in the tissues