Blood and Blood Vessels ๐Ÿ—ธ Flashcards

1
Q

blood

A

composed of
~45% erthrocytes,
<1% buffy coat (leukocytes and platelets),
~55% plasma

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2
Q

what happens when you remove the clotting factors from the plasma

A

the remains are called serum

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3
Q

how to separate blood?

A

spinning in a centrifuge

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4
Q

erythrocytes

A

Red blood cells (RBCโ€™s)
biconcave discs around 7ยตm
no nucleus or organelles once mature

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5
Q

two types of white blood cells (WBCs)

A

granulocytes
agranulocytes

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6
Q

Three granulocytes

A

neutrophils
eosinophils
basophils

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7
Q

two agranulocytes

A

monocytes
lymphocytes

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8
Q

Neutrophils

A

40-70% of WBCs
phagocytes (when activated)
single multilobed nucleus

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9
Q

Eosinophils

A

5% of WBCs
acidic granules that strain red, and a bi-lobed nucleus
Granules contain hydrolytic enzymes (inflammation)

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10
Q

Basophils

A

5% of WBCs
basic granules that stain purple/blue and a bi-lobed nucleus
Effector cells in allergic reaction

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11
Q

Monocytes

A

1-5% of WBCs
precursors of tissue microphages (phagocytes)
large kidney bean shaped nucleus

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12
Q

Lymphocytes

A

20-50% of WBCs
small spherical nucleus and basophilic (blue cytoplasm)
contain B cells and T cells

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13
Q

B Cells

A

give rise to antibody secreting plasma cells

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14
Q

T cells

A

differentiate in the thymus, many defensive functions

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15
Q

platelets

A

cell fragments that have a key role in haemostasis

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16
Q

Types of blood vessels

A

artery
arteriole
capillaries
venules
veins

17
Q

three layers of an artery

A

tunica intima
tunica media
tunica adventitia

18
Q

tunica intima

A

single layer of squamous epithelial cells (endothelium) supported by the basal lamina and a thin layer of connective tissues

19
Q

tunica media

A

predominantly made of smooth muscle fibres

20
Q

tunica adventitia

A

made of supporting connective tissues

21
Q

Structures in the arteriole

A

1 or 2 layers of smooth muscle in the tunica media, almost no tunica adventitia

22
Q

what is an arteriole

A

connects the capillaries and arteries

23
Q

structures of the capillaries

A

only tunica intima, an endothelium layer and a basal membrane

24
Q

three types of capillary

A

continuous
fenestrated
discontinuous

25
Q

continuous capillary

A

no pores, smooth basal membrane and continuous endothelium

26
Q

fenestrated capillary

A

small pores in the endothelium, intact basal membrane

27
Q

discontinuous capillary

A

large gaps straight to the lumen, larger pores in endothelium and gapping in the basal membrane

28
Q

what are venules

A

connect the capillaries to the veins

29
Q

what are the two types of venules?

A

postcapillary venules
venules

30
Q

what are postcapillary venules made from?

A

endothelium and a thin layer of connective tissue

31
Q

what are regular venules made from?

A

tunica intima and intermittent smooth muscle in the tunica media

32
Q

what are veins made from?

A

the tunica intima
a thin continuous tunica media
tunica adventitia