Block 3 Asthma

Question 1

Albuterol, Salmeterol, Salbutomol, Terbutaline, Metaproterenol (Beta-2 agonists)

Answer 1

Albuterol: fast onset & short-acting used for acute attacks
Salmeterol: short-acting

Question 2

Beta-2 antagonist OD causes bronchocon

Answer 2

Rx: glucagon, theophylline, or M-blockers

Question 3

Ipratropium (M-blocker)

Answer 3

used in pts w/ asthma & CVS disease

Question 4

Theophylline/Aminophilline

Answer 4

MOA: adenosine RB & PDEI
SE: arrhythmias, seizure, torsades

Question 5

Glucocorticoids (Beclomethasone & Flunisolide

Answer 5

MOA: decreases phospholipase A2
SE: growth suppression & delayed wound healing

Question 6

Zafirlukast (Leukotriene Receptor Blockers)

Answer 6

MOA: decreases LOX & leukotrienes

Question 7

Chromolyn & Nedocromyl (Mast Cell Stabilizers)

Answer 7

MOA: decreases histamine release from mast cells (mast cell degranulation)
(nasal spray)
Uses: seasonal allergies & asthma prophylaxis for kids