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Psychiatry MOC Review > Bipolar D/O- 14B > Flashcards

Bipolar D/O- 14B Flashcards

1
Q

Which medications are FDA approved the management of mania and maintenance treatment of bipolar disorder

A
  • Lithium
  • Risperdal consta
  • Olanzapine
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2
Q

Which medication is indicated for all phases of bipolar but only as an adjunct for maintenance

A

SEROQUEL

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3
Q

Which medications are indicated as adjuncts for the management of maintenance?

A

QUETIAPINE

ZIPRASIDONE

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4
Q

What are the indications of ABILIFY in management of bipolar disorder?

A
  • acute mania
  • mixed episodes
  • maintenance
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5
Q

What’s the other name for ASENAPINE

A

SAPHRIS

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6
Q

Medications indicated for the management of bipolar depression

A

QUETIAPIINE

OLANZAPINE+FLUOXETINE

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7
Q

Medications indicated for management of bipolar mixed episodes but not good data for maintenance

A

VALPROATE
CARBAMAZEPINE
LURASIDONE

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8
Q

Medications indicated for bipolar maintenance monotherapy

A

A ROLL

  • Abilify
  • Risperdal Consta
  • Olanzapine
  • Lithium
  • Lamictal
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9
Q

Name medications that will increase Li levels

A
  • NSAIDS
  • ACE inhibitors
  • ACE II inhibitors
  • in general diuretics double LITHIUM levels
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10
Q

Associate lithium levels with side effects

A

-0.8 target dose
-1.2 tremor
-1.5-2 seizures
->2 acute renal failure (dialysis)
>2.5 coma, death

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11
Q

General rule of thumb about using antidepressants in treatment of bipolar disorder

A

JUST DON’T FUCKING USE THEM

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12
Q

Which of the mood stabilizers has hemorrhagic pancreatitis as a potential serious side effect

A

VALPROATE

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13
Q

Approaches to treating rapid cycling bipolar disorder

A
  • Valproate more effective
  • check thyroid function
  • consider adjunctive T3 or T4 even in euthyroid
  • monitor for risk of hyperthyroidism and osteoporosis
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14
Q

List the potential serious side effects of VALPROATE

A
  • hemorrhagic pancreatitis
  • PCOS
  • thrombocytopenia
  • fatal hepatotoxicity (treat with L carnitine)
  • hyperammonemia
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15
Q

Characteristics of thrombocytopenia associated with VALPROATE

A
  • happens in 50% of the elderly
  • is dose related
  • rarely associated with bleeding
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16
Q

Describe risk of Stevens-Johnson syndrome and Tegretol

A
  • get genetic testing for HLA-B 1502 particularly in pts of east Asian descent
  • presents of this HLA is associated with increased risk of SJS
  • same as for LAMICTAL
17
Q

LAMICTAL is approved for the __________ phase of bipolar treatment

A

MAINTENANCE PHASE

Psychiatry MOC Review (60 decks)

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