Biopsychology: Biological Rhythms (L11-13) Flashcards
What are biological rhythms?
- cyclical changes in physiological systems
- evolved because the environments in which organisms live have cyclical changes
- e.g. day/night, summer/winter etc
- three types of biological rhythms, circadian, ultradian and infradian
What are circadian rhythms?
- any cycle that lasts 24 hours
- nearly all organisms possess a biological representation of the 24 hour day
- these optimise an organism’s physiology and behaviour to best meet the varying demands of the
day/night cycle
How are circadian rhythms driven?
- driven by the suprachiasmatic nuclei (SCN) in the hypothalamus
- this pacemaker (controls the rate at which something occurs)
must constantly be reset so that our bodies are in synchrony with the outside world - natural light provides the input to this system, setting the SCN to the correct time in a process called photoentrainment
- SCN then uses this info to coordinate activity of circadian rhythms throughout the body
How does the sleep wake cycle work, CR?
- light and darkness are the external signals that determine when we feel the need to sleep and when we wake up
- this rhythm dips and rises at different times of the day
- strongest sleep drives occur between 2:00-4:00am and 1:00-3:00pm
- the release of melatonin from the pineal gland is at its peak during the hours of darkness
- melatonin induces sleep by inhibiting the neural mechanisms that promote wakefulness
- light suppresses the production of melatonin
How does homeostatic control affect the sleep wake cycle, CR?
- sleep and wakefulness are also under homeostatic control
- when we have been awake for a long time homeostasis tells us that the need for sleep is increasing
- because of the amount of energy used up during wakefulness
- this homeostatic drive for sleep increases gradually throughout the day
- reaching its maximum in the late evening
- circadian rhythms keep us awake as long as there is daylight
- prompting us to sleep as it becomes dark
- the homeostatic system tends to make us sleepier the
longer we have been awake regardless of whether it is night or day - the internal circadian rhythm will maintain a cycle of 24-25 hours, even without natural
light
Circadian rhythms, +ve evaluation:
- practical application is chronotherapeutics
- the time that patients take medication is very important for treatment success
- is essential that the right concentration of drug is released in the target area of the body at the time the drug is most needed
- like the risk of heart attack is greatest during the early morning hours after waking
- medications have been developed that are taken before the person goes to sleep but are not released until the vulnerable time of 6:00 am
Circadian rhythms, -ve evaluation:
- research has not isolated people from artificial light as was believed only natural light affected
- more recent research suggests this might not be true
- Cziesler et al. altered participant’s circadian rhythms down to 22 hours and up to 28 hours using artificial light alone
= individual differences in the length of circadian rhythms
= research study found that cycles can vary from 13 to 165 hours - individual difference of when one reaches their peak
- ‘Morning people’ prefer to rise early and go to bed early whereas ‘evening people’ prefer to rise late
= studies of individuals who live in Artic regions, where the sun does not set in the summer months, show normal sleeping patterns despite the prolonged
exposure to light
= suggests occasions where the exogenous zeitgeber of light may have very little bearing on our internal biological rhythms
What are ultradian rhythms?
- cycles that span a period of less than 24 hours
What is the 5 sleep stages, UR?
- human sleep follows a pattern alternating between Rapid Eye
Movement (REM) sleep, stage five - and Non-Rapid Eye Movement (NREM) sleep, consists of stages one, two, three and four
- cycle repeats itself every 90 minutes
- each stage shows a distinct EEG pattern
- as person enters deep sleep, their brainwaves slow and their breathing and heart rate decreases
- during the fifth stage (REM sleep), the EEG pattern resembles that of an awake person
- during this stage dreaming occurs
What is the BRAC, UR?
- Kleitman (1969) referred to the 90 minute cycle found during sleep as the Basic Rest Activity Cycle (BRAC)
- suggested that this 90 minute cycle continues when we are awake
- during the day, rather than moving through the sleep
stages - we move progressively from a state of alertness into a state of
physiological fatigue - studies suggest that the human mind can focus for about 90 minutes
- towards the end of those 90 minutes the body begins to run out of resources
- resulting in loss of concentration, fatigue and hunger
Ultradian rhythms +ve evaluation:
- Ericsson et al. found support for the ultradian rhythms
- they studied a group of elite violinists
- found that among this group practise sessions were limited to 90 minutes at a time
- violinists frequently napped to recover from practise, with the best violinists napping more
- the same pattern was found among athletics, chess players and writers
- this fits with the BRAC
Ultradian rhythms -ve evaluation:
- Tucker et al. suggests that there are individual differences in
ultradian rhythms - which are biologically determined and may even be genetic in origin
- participants were studied over 11 consecutive days and nights in a laboratory environment
- researchers assessed sleep duration, time taken to fall asleep and the amount of time in each sleep stage
- they found differences in all of these characteristics
What are infradian rhythms?
- cycles than span a period of longer than 24 hours
- may last weeks, months or even a year
What is the menstrual cycle, IR?
- lasts for about a month
- considerable variations in the
length of this cycle - some women experiencing a 23 day cycle and others a 36 day cycle
- average is 28 day.
- hormones regulate the menstrual cycle
- ovulation occurs roughly halfway through the menstrual cycle at day 14
- when oestrogen levels are at their peak, and usually lasts for 16-32 hours
- after ovulation, progesterone levels increase in preparation for the possible implantation of an embryo in the uterus
Infradian rhythms, +ve evaluation:
- they can affect behaviour
- Penton-Voak found that
women express a preference for feminised male faces when choosing a partner for a long-term relationship - but they showed a preference for masculinised faces during ovulation
Infradian rhythms, -ve evaluation:
- menstrual cycle is not only governed by infradian rhythms
- when several women of childbearing age live together, and do not take oral contraceptives, their menstrual cycles synchronise
- in one study samples of sweat were collected from one group of women and rubbed onto the upper lip of another group of women
- their menstrual cycles became synchronised
- suggests that the synchronisation is affected by pheromones
- these are a chemical substance produced and released into the environment by an animal which affects the behaviour of others of the same species
What are endogenous pacemakers and exogenous zeitgebers?
- internal biological rhythms must be finely tuned in order to stay in keeping with the outside world
- to achieve this we have endogenous pacemakers (internal)
- and exogenous zeitgebers (external)
- endogenous pacemakers are body clocks (e.g. the suprachiasmatic nuclei) which regulate biological rhythms
- whereas exogenous zeitgebers are cues (e.g. light) that
entrain our biological rhythms
What does the SCN do?
- most important endogenous pacemaker is the suprachiasmatic nuclei
- this is a tiny cluster of nerve cells in the hypothalamus
- SCN plays an important role in generating circadian rhythms
- acts as the master clock, linking other brain regions that control sleep and arousal
- and controlling all other biological clocks throughout the body
How does the SCN work?
- neurons within the SCN synchronise with each other
- so that their target neurons in sites elsewhere in the body receive time-coordinated signals - these peripheral clocks can maintain a circadian rhythm
- but not for very long, which
is why they are controlled by the SCN - is possible because of the SCN’s
built in circadian rhythm - which only needs resetting when external light levels
change - SCN receives information about light levels through the optic
nerve - if our biological clock is running slow then morning light shifts the clock
What does SCN do with melatonin?
- SCN also regulates the manufacture and secretion of melatonin in the pineal gland
- via the interconnecting neural pathway
- SCN sends a signal to the pineal gland
- directing it to increase production and secretion of the
hormone melatonin at night - and to decrease it as light levels increase in the morning
- melatonin induces sleep by inhibiting the brain mechanisms that promote wakefulness
Endogenous pacemakers, evaluation:
1+ Folkard (1996) studied a university student, Kate Aldcroft, who spent 25 days in a lab
+ she had no access to the exogenous zeitgebers of light to reset the SCN
+ but at the end of 25 days her core temperature rhythm was still at 24 hours.
+ indicates that we DO NOT need the exogenous zeitgebers of light to maintain our internal biological rhythms
1- Kate Aldcroft’s sleep-wake cycle extended to 30 hours, with periods of sleep as long as 16 hours
- suggests that we DO need the exogenous zeitgebers of light to maintain our internal biological rhythms
What are exogenous zeitgebers?
- term exogenous refers to anything whose origins are outside of the organism
- exogenous zeitgebers are environmental events that are responsible for maintaining the biological clock of an organism
- most important zeitgebers for most animals is light
How does the exogenous zeitgeber of light work?
- receptors in the SCN are sensitive to changes in light levels during the day
- then use this information to synchronise the activity of the body’s organs and glands
- light resets the internal biological clock each day, keeping it on a 24-hour cycle
- a protein in the retina of the eye called melanopsin, which is sensitive to natural light, is critical in this system
What is the problem with night shift and travelling in regards to EZ?
- when people move to a night shift or travel to a country with a different time zone
- their endogenous pacemakers try to impose their inbuilt rhythm of sleep (circadian rhythm)
- but this is now out of synchrony with the exodengeous zeitgeber of light
- out of sync biological rhythms lead to disrupted sleep patterns, increased anxiety and decreased alertness and vigilance
Exogenous zeitgebers evaluation:
1+ vast majority of blind people who still have light perception have normal
circadian rhythms
+ blind people without light perception show abnormal circadian rhythms
+ shows the vital role that the exogenous zeitgeber of light levels play in maintaining our internal biological rhythms
2+ found that exposure to bright light prior to an east-west flight decreased the time needed to adjust circadian rhythms to local time
1- studies of individuals who live in Arctic regions, where the sun does not set in the summer months, show normal sleeping patterns
- despite the prolonged exposure to light
- suggests that there are occasions where the exogenous zeitgeber of light may have very little bearing on our internal biological rhythms