biology end of year final Flashcards
protein synthesis
the process of reading intructions in dna to make a polypeptide
polypeptide
-a chain of amino acids
-can bind to other and fold into a protein
transcription
dna is copied into a complementary strand of mrna
genetic code
code of instructions fo rhow to make proteins
codon
a set of 3 nucleotides on the mrna
anticodon
complementary 3 nucleotides on the trna
amino acid
-monomer (building blocks) for maing proteins
-held togeher by peptide bonds
translation
interpreting the rna message into a polypeptide to make a protein
what are the steps of transcription?
-happens in the nucleus
-gene that needs to be copied is unzipped
-the nucleotides are complementary base-paired for a new strand of mrna
-the strand is released
-dna zips back up
-molecule leaves the nucleus
what are the steps of translation?
-occurs in the ribosomes/ cytoplasm
-mrna attaches toa ribosome
-reads the mrna codon starting at aug
-trna’s drop off the amino acids that go with each codon
-the ribosome binds them together to make a polypeptide chain
what are two things on trna?
-amino acid
-anticodon
what are complementary base-pairing rules for mrna?
-a goes to u
-t goes to a
-g goes to c
-c goes to g
what is the role of mrna in protein synthesis?
-copies intruction in dna
-carries them out to the ribosomes
what is the role of trna in protein synthesis?
-binds and carries specific amino acids to the ribosome
what is the role of rrna in protien synthesis?
-along with protiens make up ribosme
-help catalyze formation of specific bonds
what would happen if there were an error in transcription or translation?
-it will get the codon wrong
-will code fo the wrong amino acid and protein
diploid
-cells with two full sets of chromosomes
-2n
-46 in humans
-somatic cells
haploid
-1 full set of chromosomes
-n
-23 in humans
-gametes/ sex cells
meiosis
process of cell division that creates gametes in the gonads
sexual reproduction
-organisms that reproduce secually fuse the genetic information from two parents
-creates offsrping that are genetically unique
fertilization
the actual fusion of the egg and sperm to form a zygote
homologus chromosomes
-chromosome paris that have the same types of genes
-1 set from mom and 1 from dad
sister chromatids
-2 identical copies of the same chromosome
-X
autosomes
-carry traits that make you who you are
-1st 22 pairs
sex chromosomes
-the 23rd pair of chromosomes
-xx or xy
-determine your sex
meiosis I
-separation of homologus chromosomes
-interphase and pmat one time
-end result is two haploid daughter cells with dupicated chromosomes
meiosis II
-separation of sister chromatids
-pmat one time
-end result is four haploid daughter cells that are genetically unique
why does meiosis go through pmat twice?
-becuase it has to divide tiwce
-the sex cells have to have half the number of chromosomes
-they will merge with another that also has half so it can have the correct number
what is the purpose of meiosis vs the purpose of meisosis?
-meiosis: make sex cells for reproduction
-mitosis: make somatic cells for growth and repair
what would happen if there was a mistake in meiosis vs a mistake in mitosis?
-meiosis: cause your cell toe end up with an extra chromosome (or your baby)
-mitosis: cause the number of the chromosomes in your cells to be off forever
interphase I
-dna replication
-cell growth
prophase I
-crossing over
-nuclear membrane breaks down
-homologus chromosomes pair up
-spindle fibers appear
metaphase I
-homologus chromosomes line up in the middle of the cell
anaphase I
-homologus chromosome pairs separate
telophase I
-chromosomes gather at poles
-nuclear membrane may return
cytokinesis I
-cytoplasm divides into two cells
prophase II
-nuclear membrane reforms
-spindle fibers form
-spindle fibers attach at chromosomes
metaphase II
-sister chromatids line up single file
anaphase II
-sister chromatids separate
telophase II
-nuclear membrane forms around each sert of chromosomes
-spindle fibers dissolve
cytokinesis
-cytoplasm divides each cell into two
-creates 4 cells
meiosis vs mitosis: what, when, where, result, and type of reproduction
-mitosis what: creation of diploid somatic cells
-meiosis what: ceration of haploid sex cells
-mitosis when: throughout your life
-meisosi when: females before you’re born, men throughout your life
-mitosis where: throughout your body
-meiosis where: in ovaries and testes
-mitosis result: 2 identical diploid somatic cells
-meiosis result: 4 unique haploid sex cells
-mitosis reproduction: asexual
-meiosis reproduction: sexual
gene
a section of dna that provides the instructions for making a protein
alleles
different versions of the same gene
homozygous
-2 of the same alleles
-ex. AA or aa
heterozygous
-2 different alleles
-ex. Aa
dominant
if present, allele will always have that trait expressed/ seen
recessive
allele will only have htat trait expressed when the dominante allele is not present
genotype
-the actual alleles inherited
-ex. FF, Ff, and ff
phenotype
-the physical trait seen
-ex. purple flowers
law of segregation
-when chromosomes separate in meisos each gamete will recieve only one chromosome from each pair
law of independent assortment
-the assortment of chromosomes for one trait doesn’t affect the assortment of the chromocomes for another
chromosome tgheory of inheritance
-genes are located on chromosmes and the behavior of chromosomes during meisois accournts of inheritance pattersn
incomplete dominance
-the heterozygous phenotype is somehwere between the two homozygous phenotypes
-neither allele is domiant or recessive
-ex. HH is straight hair, H’H’ is curly hair, and HH’ is wavy hair
-ex. pink flowers
codominance
-both traits are fully and separetly expressed
-ex. WW is white cow, BB is black cow, BW is spotted cow
-ex. speckled chicken
-ex. blood type (AB is fully A and fully B)
multiple alleles
-having more than two alleles for none gene
-ex. A, B, and i alleles for blood type
polygenic traits
-a trait produced by two or more genes
-usually shows a range in phenotype
-ex. height
-ex. eye color
linked genes
-genes that are physically loctaed on the same chromosome will be inherited together
-ex. blond hair and blue eyes
epistatis
-when one gene overshadows another gene and blocks the output
-ex. albinism
carrier
-a person that has the gene for a trait or disease but doesn’t show it
-ex. having one copy of the trait for color blindness
sex linked genes
-genes that travel on the c chromosome
-boys only need 1 copy to be affected
mutation
-any change in dna
-ex. the order of the nucleotide bases /letters
mutagen
-chemicals that can cause dna mutations
-ex. radiation
gene mutation
-happen during dna replication
-cause a change to the orginal dna sequence
point mutation
-substitute one nucleotide for another
-ex. sickle cell anemia
frameshift mutation
-the insertion or deletion of a nucleotide
-ex. ATTACC—> ATACC
chromosomal mutation
-often happen during meiosis
-changing the number or location of genes
-ex. down syndrome
duplication
-changes the size of chromosomes
-results in multiple copies of a single gene
translocation
-pieces of non-homologus chromosomes exchange segments
-can happen during crossing over
nondisjunction
-chromosomes do not separate correctly during anaphase
-results in one or three chromosomes per cell
pedigree
-char used ot trace the phenotypes and genotypes in a family
-can help determine whether people carry diseases or traits
is a mutation in a somatic cell or a gamete worse? why?
-gamete
-the mutation will be in every cell of the baby’s body
-a mutation in a somatic cell will only be in that cell
is a mutation ina a gene or chromosome worse? why?
-chromosome
-there are many genes on a chromosome
-it will effect more dna
autosomal recesive trait (pedigree)
-most common inheritance patter for genetic diseases
-diesease will be rare in family
-often skips generations
ex. sickle cell anemia, cystic fibrosis
autosomal dominant
-disease will be common in family
-never skips a generation
-ex. huntington’s dieseas, neurofibromatosis
sex-linked recessive
-diesease will be rare in the family
-more males will be affected than females
-affected fathers do not pass on to their sons (they have to pass on they y, the mom gives the x)
-ex. meophilia, colorblindness
evolution
-the process of biologiacl change in populations over time
-causes descendants to e genetically different from their ancestors
microevolution
-occurs on a small scale
-affects a sigle population
macroevolution
-occurs on a large scale
-changes across several populations
natural selection
-organisms with the “best” traits will live longer and reproduce more
-will cause changes in the population over time
-acts on traits that are heritable
fittness
-a measure of how well you can survive in your environment
what are the 4 principles of natural selection?
-overproduction of offsrping
-variation
-adaptation
-descent with modification