Biology - Chapter 11.4: Nervous System Flashcards
Axon hillock
- Area where the axon is connected to the cell body
- Responsible for summation of graded potentials
Myelin sheath
- Fatty insulation of the axon that speeds up action potential propagation by stopping ion exchange
- CNS: oligodendrocytes
- PNS: Schwann cells
Nodes of ranvier
- Gaps between myelin sheath where ion exchange occurs
- Propagation of action potential occurs here
Saltatory conduction
Propagation of action potential along myelinated axons from one node of Ranvier to the next node
Steps of an Action Potential
1) At resting potential, membrane potential is around -70 mV and is maintained by Na+/K+ ATPases (3 Na+ ions out, 2 K+ ions in). K+ leak channels also maintain resting potential.
2) Stimulus causes threshold potential reached (-55mV), voltage-gated Na+ channels open, resulting in depolarization = action potential.
3) Repolarization occurs as voltage-gated K+ channels open, letting K+ out. Membrane potential becomes negative again.
4) Hyperpolarization occurs as the membrane potential becomes even more negative than normal resting potential. Results in a refractory period = no action potential can be fired.
5) Membrane potential returns to normal resting potential through the pumping of Na+/K+ ATPases and K+ leak channels
Absolute refractory period
- No other action potential can be fired, no matter how powerful
- Due to the inactivation of voltage-gated Na+ channels after they open
Relative refractory period
-A stronger stimulus could cause another action potential to fire
Steps of Synaptic Transmission
1) Action potential reaches presynaptic axon knob, opening voltage-gated calcium channels and releasing Ca2+ ions into neuron
2) Ca2+ ions cause synaptic vesicles to fuse and undergo exocytosis: releasing neurotransmitters into synapse
3) Neurotransmitters bind to ligand-gated ion channels, producing a graded potential
4) Graded potentials summate at the axon hillock and a potential action potential is fired if threshold potential is reached.
EPSP
- Excitatory postsynaptic potential
- graded potential that depolarizes membrane
- Na+ ion gates to open and let Na+ ions flow into the cell
IPSP
- Inhibitory postsynaptic potential
- graded potential that hyperpolarizes the membrane
- K+ ion gates open and let K+ ions flow out of cell
Microglial cells
Macrophages that protect the CNS
Macroglial cells
- Astrocytes
- Schwann cells (PNS)
- Oligendrocytes (CNS)
- Satellite cells
- Ependymal cells
Astrocytes
- Form the blood-brain-barrier
- help recycle neurotransmitters
- provide blood supply to CNS
Satellite cells
- help recycle neurotransmitters
- provide blood supply to PNS
Ependymal cells
-secrete cerebrospinal fluid which cushions the CNS
Frontal lobe
- Higher function processes such as decision making, problem solving, judgement, planning ahead, consequences
- Works with limbic system for memories and emotions
- Attention/concentration
Temporal lobe
- Speech/language
- Hearing
Occipital lobe
-Vision
Parietal lobe
- Spatial/visual perception
- Touch/pain/temperature sensation and integration