BIOL 202 4th exam Flashcards

1
Q

Trypanosomes (What are they?)

A
  • Trypanosomes are vector-borne parasites - (they must have a vector)
    ○ Vector: any living organism that can pass a disease from one organism to another
    § (this means we cant simply get them from the environment)
    They also have a kinetoplast that houses their DNA (in the pathogen
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2
Q

Sleeping sickness (what causes it and what are its symptoms)

A

○ Sleeping sickness - vector = tsetse fly (only in southern Africa)
§ Joint pain
§ Confusion
§ Poor coordination
§ Trouble sleeping
§ Can cause death if untreated
§ DEADLY

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3
Q

Chagas’ disease (What causes it and what are its symptoms)

A

○ Chagas’ disease - vector = kissing bug (found in multiple continents)
§ Swollen lymph nodes
§ Headaches
§ Fever

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4
Q

Leishmaniasis (What causes it and what are its symptoms)

A

○ Leishmaniasis - vector = sand fly (mostly in south America)
§ Skin sores
§ Visceral leishmaniasis
□ Weight loss
□ Enlarged liver and spleen
§ Leads to death if untreated
§ DEADLY

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5
Q

Helminth (what are they?)

A

Parasitic worms are called helminths

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6
Q

Nematodes (Characteristics)

A

○ Nematodes (roundworms)
§ Cylindrical
§ Have a digestive tube that ends in an anus (has outlet)

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7
Q

Trematodes (Characteristics)

A

○ Trematodes (flukes)
§ Oval shaped
§ Have digestive tube that ends in a cecum (no outlet)
§ Hermaphroditic
§ Slow and flat

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8
Q

Cestodes (Characteristics)

A

○ Cestodes (tapeworms) are parasitic flatworms
§ Absorb nutrients through their skin

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9
Q

Nematodes (pinworm characteristics)

A
  • Pinworms
    ○ Small, white nematodes of the species enterovirus vermicularis
  • About the length of a staple
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10
Q

Nematodes (Hookworms Characteristics)

A
  • Hookworms - type of nematode
    ○ Travel through blood to lungs
    ○ Penetrate the alveoli in the lungs
    ○ Host coughs and parasite moves to the throat and gets ingested
    ○ When they get into the small intestine they latch onto the intestinal lining and suck blood
    ○ Offspring exit in the host feces
    ○ They are common in pets
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11
Q

Nematodes (Roundworms Characteristics)

A

○ Ascaris lumbricoides (THIS IS THE MOST COMMON PARASITE IN HUMANS)
§ Eggs ingested from soil by animals (humans usually come in contact from meat
§ Worms increase in size in the digestive tract
§ Has an anus
Worms may also invade the lungs or other organs, causing life threatening damage

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12
Q

Trematodes (Flatworms characteristics)

A
  • Trematodes (flukes)
    ○ Flatworms (platyhelminths)
    § Internalized mouth
    § Pharynx
    § Digestive tube, but the tube ends in one or more pouches called caeca
    § Dont have an anus
    ○ Usually have two suckers
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13
Q

Cestodes (Tapeworms Characteristics)

A
  • Cestodes: tapeworms
  • Transmitted as larvae in uncooked meat
  • Composed of a head and successive segments
  • Commonly grow 2-15 meters in length
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14
Q

Algae (Characteristics)

A
  • Algae are protists that conduct photosynthesis by using chloroplasts
    ○ Photolithoautotrophic
    ○ Primary producers
    ○ Prey species
    ○ Mixotrophic species act as primary producers and consumers
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15
Q

What are the two main lineages of Algae?

A
  • Two main lineages:
    ○ Green algae (Chlorophyta)
    ○ Red algae (Rhodophyta)
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16
Q

What is unique of brown algae?

A
  • Brown algae (like kelp)
    ○ Tend to be multicellular
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17
Q

Primary endosymbiosis (What is it?)

A
  • Primary endosymbiosis
    Prokaryote + eukaryote = eukaryote
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18
Q

Secondary endosymbiosis (What is it?)

A
  • Secondary endosymbiosis
    Eukaryote + eukaryote = eukaryote
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19
Q

Is red tide (Karenia brevis) toxic?

A

yes, it is, and it can harm species, but it does glow.

20
Q

Viruses (General characteristics)

A
  • Viruses are ubiquitous
    ○ Infect every taxonomic group of organisms
    ○ Noncellular particle with a genome contained by capsid
    § Noncellular - means they do not have the machinery to replicate their own genome, perform their own metabolic functions, etc.
    □ Thus they must have a host
    ○ Spike proteins - help plug membrane into the capsid and help virus attach to host cell
    ○ ENVELOPE IS NOT PRESENT IN ALL VIRUSES
21
Q

Virions (What are they?)

A

Virions - what we call virus particles

22
Q

Viral load (What is it?)

A
  • Viral load - number of virions that can be found in the body
    ○ Higher viral load = typically worse infection (but not always)
    § Example: higher viral load of COVID virions doesnt necessarily lead to worse symptoms
23
Q

When do PCOT tests exhibit positive results?

A
  • Point of care tests (PCOT) only exhibit positive results if the viral load is high enough
24
Q

Infectious dose (What is it?)

A
  • Infectious dose - the # of virions needed to cause infection
    ○ Varies with virus type
    § Example: Rhinovirus (common cold) requires 10 virions to cause disease; HIV (can lead to AIDS) requires only one virion to cause disease
25
Transmission (What is it?)
- Transmission: the process of a virus reaching a new host ○ Things such as masks, hygiene, space, environmental conditions, and vaccines can lower transmission rates
26
Infection rate (What is it?)
- Infection is the rate at which people actually get sick
27
Host range (What is it?)
Host range: the group of species the virus can infect
28
Antigenic drift (what is it?)
- Antigenic Drift: rapid mutation in genetic material coding for antigens (external proteins)
29
The Red Queen Hypothesis (What is it?)
It is a loop that goes like - host is defended - virus cant replicate - virus mutates - host doesn't recognize new strain - host immune system adapts
30
Levels of virus evolution (Host community)
○ Within a host community - Evolve to infect different species
31
Levels of virus evolution (Species population)
○ Within a viral species population - Strains of the same virus evolve that vary in infectivity and virulence
32
Levels of virus evolution (Individual organism)
○ Within an individual organism - Viruses evolve variants that resist therapeutic agents
33
Steps of viral replication (1-3)
○ Steps of general viral replication: 1. Host attachment 2. Enter host 3. Uncoat
34
Steps of viral replication (4-6
4. Express viral proteins to hijack host machinery 5. Use host machinery to assemble more of its viral genome 6. Release and transmission
35
Antibiotic, antiviral, antifungal, antiparasitic. (What are each of the definitions?)
§ Antibiotic: against bacteria § Antiviral: against viruses § Antifungal: against fungus § Antiparasitic: against parasites
36
Baltimore model (Group one)
dsDNA - goes through basic DNA replication process
37
Baltimore model (Group 2)
ssDNA - Bad; makes itself double stranded then uses RNA polymerase to become mRNA
38
Baltimore model (Group 3)
dsRNA - Bad; negative strand duplicates into positive (mRNA) strand; positive strand turns straight into protein
39
Baltimore model (Group 4)
ssRNA (+) - Bad; can go straight to protein; also can create negative strand and from that a positive strand (which is mRNA)
40
Baltimore model (Group 5)
ssRNA (-) - Bad; goes to positive strand (mRNA) to protein; can also go back to negative strand
41
Baltimore model (Group 6)
ssRNA (+) Uses reverse transcriptase to create dsDNA; can also go back to positive single strand RNA (mRNA)
42
Baltimore model (Group 7)
dsDNA dsDNA turns into +ssRNA (mRNA) and into protein; uses reverse transcriptase to go back into dsDNA
43
Bacteriophage (Characteristics)
- Viruses that infect bacteria ○ Being studied for phage therapy! § Using phages to fight off pathogenic bacteria - essentially inject bacteriophage into patient to attack bacterial infection
44
Bacteriophage (parts)
- Structure ○ Head § Icosahedral protein package § Contains genetic material ○ Tail § Injects genetic material into host cells
45
Lytic infection (Characteristics)
- Lytic infection ○ Virulent phage ○ Lysis (rupture) of host cell § Virus infects § Cell lyses § Virus spreads
46
Lysogeny (Characteristics)
- Lysogeny ○ Phage genome integrates in host cell ○ Host cell replicates with vital components ○ The viral genome components trigger a lytic cycle over time § Virus infects § Integrates in host genome § Stays until stressful conditions § Triggers lytic infection § Virus spreads
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