Bio 7- Mass transport Flashcards
How many oxygen molecules can bind to a single molecule of haemoglobin?
4 oxygen molecules
What is the function of haemoglobin?
To transport oxygen from the lungs to the body
What does affinity mean?
How readily haemoglobin binds to and releases oxygen
What does loading/associating mean?
Haemoglobin binds with oxygen and this takes place in the lungs
What does unloading/dissociating mean?
Haemoglobin released the oxygen and this takes place in the tissues
What does it mean if haemoglobin has a high affinity for oxygen?
It binds with oxygen more easily and releases it at the tissues less easily
What does it mean if haemoglobin has a low affinity for oxygen?
It binds with oxygen less easily and releases it at the tissues more easily
Explain the oxygen dissociation curves (4 marks)
- the shape of the haemoglobin molecule makes it hard for the first oxygen to bind, so at low oxygen cones little oxygen binds to haemoglobin
- binding of the first oxygen molecule changes haemoglobin quaternary shape, this change makes it easier for other oxygen molecules to bind.
- takes a smaller increase in partial pressure of oxygen to bind the second oxygen molecule compared to the first one
- It is harder for the 4th oxygen molecule to bind due to probability as there aren’t as many binding sites that are free.
Why do different haemoglobin’s have different affinities for oxygen?
Due to the shape of the molecule. Each species produces a haemoglobin with a slightly different amino acid sequence which means the haemoglobin of each species has a different tertiary and quaternary structure.
When carbon dioxide conc is increased what is the effect on haemoglobin?
haemoglobin more readily releases its oxygen
Explain the process that ensures there is always sufficient oxygen for respiring tissues. (5 marks)
- The higher the rate of respiration
- the more carbon dioxide the tissues produce
- the lower the pH
- the greater the haemoglobin shape change
- the more readily oxygen is unloaded
- the more oxygen is available for respiration
What is a double circulatory system?
Where blood is confined to vessels and passes twice through the heart for each complete circuit of the body.
Where are the atrioventricular valves located?
Between each atrium and ventricle
What do the atrioventricular valves do?
They prevent the back flow of blood into the atria when the ventricles contract
What are the vessels connecting the heart to the lungs called?
Pulmonary vessels
What is the aorta and where is it?
Its connected to the left ventricle and carries oxygenated blood to all parts of the body expect the lungs.
What is the vena cave and where is it?
Its connected to the right atrium and bring deoxygenated blood back from the tissues of the body
What is the pulmonary artery and where is it?
It is connected to the right tentacle and carries deoxygenated blood to the lungs, where its oxygen is replenished and its carbon dioxide.
What is the pulmonary vein and where is it?
Its connected to the left atrium and brings oxygenated blood back from the lungs.
What are coronary arteries?
The heart muscle is supplied by its own blood vessels called coronary arteries
Where are the coronary arteries?
They branch off the aorta shortly after it leaves the heart