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Microbiology 145 > Bio 145 Quiz 9 (ch 17-19) > Flashcards

Bio 145 Quiz 9 (ch 17-19) Flashcards

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Biology 101 flashcards
1
Q 
With an antibody sandwich ELISA, the plates are coated with what molecule or substance?
A. Antigen
B. Gelatin
C. Antigen specific antibodies
D. Bacteria
A

C. Antigen specific antibodies

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2
Q 
This type of assay uses a porous material like filter paper containing antibody bound with a colored substrate and an example of this is a pregnancy test.
A. ELISA
B. Direct fluorescence
C. Immunoblot
D. Immunochromatographic assay
A

D. Immunochromatographic assay

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3
Q

If no color develops in an ELISA, what can you conclude
A. the test is negative
B. The tets is positive
C. Toxin has been released
D. Labeled enzyme has reacted with substrate

A

A. the test is negative

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4
Q 
What are the two main steps in type 1 hypersensitivity?
A. Swelling and rash
B. Sensitization and degranulation
C. Cell killing and hemolysis
D. Escape phagocytosis and inflammation
A

B. Sensitization and degranulation

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5
Q

What mechanism leads to type 2 hypersensitivity?
A. release of inflammatory molecules in response to an antigen
B. destruction of cells by complement and antibodies
C. Circulation of immune complexes in the bloodstream
D. Lack of phagocytosis

A

B. destruction of cells by complement and antibodies

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6
Q

What happens if a blood transfusion recipient has preexisting antibodies to foreign blood antigens?
A. Foreign transfused blood cells circulate normally
B. Hemolysis
C. Blood clotting
D. Both B and C

A

D. Both B and C.

B. Hemolysis, C. Blood clotting

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7
Q 
Which of the following is an example of type 3 or immune complex mediated hypersensitivity?
A. rheumatoid arthritis
B. Reaction to a blood transfusion
C. Reaction to a bee sting
D. Reaction to pet dander
A

A. rheumatoid arthritis

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8
Q 
Type 4 hypersensitivity is also known as \_\_\_\_ because it provokes inflammation due to interaction of antigen, antigen presenting cells, and T-cells at the site after 12-24 hours
A. Cytotoxic
B. Immediate
C. Delayed or cell mediated
D. Immune complex mediated
A

C. Delayed or cell mediated

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9
Q 
Which of the following is NOT an example of type 4 hypersensitivity?
A. TB test
B. Contact dermatitis 
C. Graft rejection
D. Peanut butter allergy
A

D. Peanut butter allergy

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10
Q 
When the immune system produces antibodies and cytotoxic T cells to target normal body cells it is called:
A. Hypersensitivity
B. Autoimmunity
C. Immunodeficiency
D. Infection
A

B. Autoimmunity

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11
Q

The cause or etiology of autoimmunity is largely unknown but which of the following is NOT a hypothesis?
A. Failure of Treg or CD95 control
B. Genetic factors
C. Y chromosome or paternal factors
D. Molecular mimicry of pathogen antigens similar to self antigens

A

C. Y chromosome or paternal factors

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12
Q 
Which of the following is a target of autoimmune attack?
A. Endocrine glands
B. Connective tissue
C. Epithelial cells
D. Both A and B
A

D. Both A and B

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13
Q 
Which autoimmune disease involves destruction of nervous tissue?
A. Hemolytic anemia
B. Type 1 diabetes
C. Multiple sclerosis
D. rheumatoid arthritis
A

C. Multiple sclerosis

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14
Q 
If a child's thymus gland fails to develop properly, this can lead to a deficiency in:
A. T cells
B. B cells
C. Monocytes
D. Rheumatoid arthritis
A

A. T cells

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15
Q 
Staphylococcus aureus can cause all of the following skin diseases EXCEPT:
A. Acne
B. Folliculitis
C. Scalded skin syndrome
D. Impetigo
A

A. Acne

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16
Q 
Pathogenic Streptococcus pneumoniae colonizes the:
A. skin
B. lung
C. mouth
D. urinary tract
A

B. lung

17
Q

Tetanospasmin, a toxin produced by clostridium tetani causes tetanus by acting on neurons to block the ____ causing ____
A. acetylcholine, flaccid paralysis
B. Release of inhibitory neurotransmitters, rigid paralysis
C. Phagolysosome formation, intracellular parasitism
D. Complement, lack of complement opsonization

A

B. Release of inhibitory neurotransmitters, rigid paralysis

18
Q

The difference between hypersensitivity and autoimmunity is that hypersensitivity _______.
A. Involves T cells, whereas autoimmunity involves B cells
B. Involves reaction to foreign molecules, whereas autoimmunity involves reaction to self molecules
C. has treatment options, whereas there are no treatment options for autoimmune diseases
D. Does not lead to death, whereas there is the risk of death with autoimmune disease

A

B. Involves reaction to foreign molecules, whereas autoimmunity involves reaction to self molecules

Microbiology 145 (21 decks)

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