Basic Pharmacology Flashcards

1
Q

We use what from Animals to provide a source for drugs?

A

Hormones

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2
Q

Thrombin (thrombogen) is made from

A

cattle

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3
Q

what comes from the urine of pregnant horses?

A

Conjugated estrogen (Premarin)

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4
Q

What is an example of an antacid made from minerals?

A

Calcium (tums), magnesium hydroxides (mylanta)

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5
Q

What is an example of an antimicrobial made from minerals?

A

Silver salts (silvadene cream)

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6
Q

How are synthetic drugs made?

A

In chemical laboratories from chemicals

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7
Q

Most common drugs are either made as

A

Synthetic or Semisynthetic

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8
Q

Humulin is

A

Human insulin

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9
Q

Nutropin is

A

Human growth hormone

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10
Q

Thyrogen is

A

Human thyroid-stimulating

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11
Q

How are biotechnology drugs given?

A

By injection only

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12
Q

What are the four drug classifications?

A

Therapeutic action, physiologic action, affected body system, and chemical type.

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13
Q

define therapeutic action

A

what the drug does for the patient

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14
Q

define physiologic action

A

what the drug does in the body

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15
Q

define affected body system

A

what the drug affects

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16
Q

define chemical type

A

what the drug is

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17
Q

“An” means

A

without

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18
Q

“esthesia” means

A

sensation

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19
Q

“anesthesia” means

A

without sensation

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20
Q

Why does the DEA require specific information on a script?

A

For controlled substances

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21
Q

what does PRN stand for

A

When needed

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22
Q

what are the four drug FORMS?

A

Solid, Semisolid, Liquid, Gases

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23
Q

what FORM is rarely used in the OR?

A

Solid

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24
Q

What does freeze dried and powders require to make a solution?

A

Sterile water or saline

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25
What are the liquid FORMS?
Solutions, suspension, and emulsion
26
What is suspension
a drug undissolved in liquid
27
What is emulsion?
a mixture of water and oil bound together with an emulsifier
28
What are examples of gases?
Nitrous oxide (N20) and suprane (desflurane)
29
cap=
capsule
30
ggts=
drops
31
soln=
solution
32
susp=
suspension
33
tab=
tablet
34
ung=
ointment
35
What are the two drug administration routes?
Enteral and parenteral
36
What is a parenteral route?
Any route other than by way of the digestive tract
37
What administration route is absorbed slowly through the skin or absorbs rapidly when applied to blood supply or mucus membrane?
Topical (parental)
38
What administration route is injected beneath the skin layer in the subcutaneous tissue?
Subcutaneous
39
What administration route are given in large muscle masses?
Intramuscular
40
intravenous=
absorbs directly into the bloodstream
41
Interthecal=
into spinal subarachnoid space
42
The study of how the body processes drugs
Pharmacokinetics
43
The amount of drug that reaches the site of action depends on
the patients circulatory system
44
All drugs eventually make it where?
To the liver.
45
The study of how drugs exert their effects on the body on both molecular and physiological levels
pharmacodynamics
46
what is an agonist?
an attraction
47
multiple drugs can do what?
cancel each other out to reduce each others effects
48
what is an antidote for a patient on warfarin that is over anticoagulated?
Vitamin K
49
What cancels out the effects of warfarin?
Vitamin K
50
the time between onset and disappearance of drug effect
duration
51
predictable but unintended effects of a drug
side effect
52
An undesired potentially harmful side effect of drugs
adverse effect
53
an adverse effect resulting from previous exposure to the drug or similar drug.
hypersensitivity
54
another type of adverse effect. Rare, unpredictable and unavoidable
idiosyncratic effect
55
a drug that enhances the effect of another drug
synergist
56
a reason or purpose for giving the medication
indication
57
a reason against giving a medication
contraindication
58
the time between administration of a drug and the first appearance of the effects
onset
59
BID=
twice per day
60
q=
every
61
qh=
every hour
62
q2h=
every 2 hours
63
qid=
four times a day
64
PO=
by mouth
65
KVO/KTO=
keep vein open/to keep open
66
sos=
once if necessary
67
Drugs that are synthesized from laboratory chemicals. ex. penicillin was extracted from mold
Synthetic drugs
68
the process by which a drugs chemical composition is changed usually occurs in the liver.
biotransformation (metabolism) Factors affecting biotransformation? Liver "health" ex. cirrhosis and first-pass effect (where most of the drug is broken apart by the liver before its activated) Biotransformation may also take place in plasma, lungs, GI tract, or kidneys.
69
drugs being given all at once as opposed to by flow infusion
bolus
70
What is the most common emulsion used in surgery?
Propofol (Diprivan)
71
what are 3 variations of the topical route?
1. Instillation into a mucous membrane BY eye, nose, urethra ex.) tetracaine (Pontocaine) - eyes * oxymetazoline (Afrin) - nasal cavity * lidocaine (Xylocaine) jelly - numbs urethra 2. Inhalation, ex. inhaling anesthetic gases or asthmatic drugs - inhaler 3. Contrast media - chromotubation (pushed into blood stream)