Antineoplastic Chemotherapy Agents Flashcards

1
Q

A group of disease characterized by an uncontrolled growth of cells. Nearly 1/3 of all Americans are affected by this during their life, second cause of death in the US

A

cancer

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2
Q

When the normal rate of cell division is disrupted and not controlled, an abnormal growth of cells is formed. This abnormal growth is called a tumor or _______.

A

Neoplasm

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3
Q

Neoplasm (tumor) may be ______, which means they resemble normal tissue, grow slowly, are highly organized cells, and do not normally spread into surrounding tissue.

A

benign

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4
Q

Neoplasms (tumor) may also be _______, or cancerous. These cells are unorganized and immature, multiply rapidly, and invade surrounding tissue.

A

Malignant

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5
Q

The original site of the tumor is called

A

primary site

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6
Q

When malignant cells travel through the circulatory or lymphatic system and spread to other areas of the body, they form another tumor called a _______.

A

Metastasis

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7
Q

Each new location of cancer is referred to

A

secondary site

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8
Q

agents that fight cancer, can be used as systemic treatment in the primary or main tumor, and in tis metastases.

A

Anitneoplastic agents

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9
Q

Anitneoplastic agents are ________ and thus harm normal cells as well as malignant ones. They are given on a scheduled regimen to allow normal cells to recover in between therapy.

A

cytotoxic

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10
Q

______ (Mutamycin, MTC) is an anti-tumor antibiotic that is used to prevent recurrence of any eye growth called _________. It can also be used to treat or shrink cancerous growths on the eye.

A

Mitomycin, pterygium

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11
Q

Hormone used as steroids are prednisone, mtheylprednisolone (_____), and dexamethasone (______).

A

Solu-Medrol, Decadron

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12
Q

is an experimental technique that uses genes to treat or prevent disease.

A

Gene therapy

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13
Q

What is the abatement (stopping) of symptoms and possible cure of the disease.

A

Remission

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14
Q

What means the relief of symptoms without cure?

A

Palliation

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15
Q

What is methotrexate used for?

A

Ectopic pregnancy

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16
Q

What are the least toxic of the anticancer drugs and are used in combination therapy for treating various cancers?

A

Hormones and hormone antagonists

17
Q

What is used to boost the immune system?

A

Filgrastim (Neupogen)

18
Q

Another area of science and technology that focuses on atomic- and molecular-scale structures is

A

Nanotechnology

19
Q

What drugs are the largest group of anticancer agents and are toxic to tissues that grow rapidly?

A

Alkylating

20
Q

In women, the leading sites of fatal cancers

A

Lung, breast, colon, and rectum.

21
Q

In men, leading sites of fatal cancers

A

Lung, prostate, colon, and rectum

22
Q

newer alkylating agent can be used to treat brain tumors?

A

Temodar