Basal Ganglia (NUCLEI) Flashcards

1
Q

What structure regulates movement fine-tuning by projecting to the thalamus and the tegmentum of the brainstem?

A

The basal ganglia (nuclei)

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2
Q

The basal ganglia is composed of 4 things:

A
  1. Corpus striatum (caudate and putamen)
  2. Globus pallidus
  3. Substantia nigra
  4. Subthalamic nucleus
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3
Q

caudate + putamen = ?

A

striatum

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4
Q

putamen + globus pallidus = ?

A

lenticular (or lentiform) nuclei

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5
Q

What structure is in both the striatum and the lenticular (or lentiform) nuclei?

A

putamen

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6
Q

What structure regulates fine movement by exerting inhibitory control of the motor cortex?

A

the striatum

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7
Q

The striatum is divided into the __________________ and the _______________. These structures are separated by thick, vertical fibers known as the _________________________.

A

caudate nucleus and putamen
internal capsule

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8
Q

The internal capsule are cortical projections from the ___________________ to the ________________.

A

motor cortex to the spinal cord

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9
Q

The majority of them become the _____________________ and regulate ______________.

A

corticospinal tract
movement

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10
Q

Which structure involves extensive outputs to thalamus and motor cortex?

A

Internal segment (GPi)
[globus pallidus]

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11
Q

What structure projects lateral inhibitory fibers to the GPi ?

A

External segment (GPe)
[globus pallidus]

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12
Q

What is a dopaminergic nucleus that regulates inhibition of motor activity, motor planning, and reward-seeking behaviors?

A

Substantia Nigra

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13
Q

Many of the substantia nigra’s effects are mediated through control of the _________________ ?

A

striatum

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14
Q

Degeneration of the substantia nigra leads to what disease?

A

Parkinson’s disease

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15
Q

The substantia nigra is anatomically and functionally divided into two things:

A
  1. Pars compacta (SNpc)
  2. Pars reticulata (SNpr)
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16
Q

The pars compacta projects dopaminergic fibers to the _______________, activating the ___________________ circuit

A

striatum
basal ganglia

17
Q

Pars reticulata (SNpr) projects ______________ to other brain structures to tonically _________the circuit

A

GABAergic fibers
inhibit