BAD_EO Flashcards
What are the specifiers of a manic episode? (Total=7)
Anxious distress Psychothic features Mixed features Peripartum onset Catatonia Remission Severity
What are the specifiers of depressive episode? (Total=9)
anxious distress Psychotic features Mixed features Atypical features Melancholic features Peripartum onset Catatonia Remission Severity
What are the periods where suicides are higher?
During hospital admissions (14%) and six weeks after discharge (26%)
What are the main factors associated with suicide deaths ? (Total=8)
Male gender
Older age
Current episode of depression(70% of deaths and suicide attemps occur during this phase), mixed or manic with psychotic features
Hopelessness or psychomotor agitation during the current episode
Comorbidity of anxiety disorder
First-degree relatie with mood disorder or suicide
Prior suicide attempt
Psychosocial precipitant present within the first week of death
What are the features suggestive of bipolarity? (Total of 9)
Hypersomnia
Hyperphagia
Other atypical depressive sx such as leaden paralysis
Psychomotor retardation
Psychotic features and-or pathological guilt
Lablility of mood: irritability;racing thoughts;psychomotor agitation
Early onset of depression (avant 25 ans)
Multiple prior episodes (plus que 5)
Positive family hx of BAD
What is first-line treatment of adjunctinve psychological treatment of bipolar disorder?
Psychoeducation only for maintenance (level 2)
What is second-line recommendation for adjunctive psychological treatment for bipolar disorder?
CBT and Family-focused therapy for maintenance and depression
What is third line recommendation for adjunctive psychological treatment of bipolar disorder?
IPSRT for maintance and depression
Peer support only for maintenance
What are first line monotherapy agents for mania? (Total=8)
Lithium Quetiapine Epival Asenapine Aripiprazole Paliperidone Risperidone Cariparazine
What are first-line combination therapy for mania? (Total=4)
Quetiapine+Li-DVP
Aripiprazole +Li-DVP
Risperidone +Li-DVP
Asenapine +Li-DVP
Percentage of response in mania?
50% to monotherapy within 3-4 weeks. 20% more to combination thx.
Lithium is preferred over epival when individual displays which features?
Classic euphoric grandiose mania
Few prior episodes of illness
A mania-depressive-euthymic course of disease
Family hx of lithium response
Epival is preferred over lithium in individuals who display which features?
Equally effective in those with classical and dysphoric mania Multiple prior episodes Predominant irritable mood Comorbid SUD History of head trauma
Carbamazepine may be preferred in individuals who display which features?
History of head trauma
Comorbid anxiety and substance use
Schizoaffective presentation with mood-incongruent delusions
Negative hx of BAD in first-degree relatives
Which tx has evidence for mixed features in mania?
Combination therapy with atypical antipsychotics and epival.
Asenapine, aripiprazole, olanzapine and ziprasidone have been shown to be equally effective in tx mania with mixed features.
