Anxiety_EO Flashcards

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1
Q

What is not recommended for the pharmacological treatment of panic disorder?

A

Buspirone, propranolol, trazodone and tiagabine

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2
Q

What are first line pharmacological tx of panic disorder? (Total=7)

A

Citalopram, escitalopram, prozac, paxil, luvox, zoloft and effexor XR

There is evidence that short-term (less than 8 weeks) of adjunctive clonazepam at the initiation of SSRI can lead to a more rapid response

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3
Q

Name some of the second line pharmacological agents used in panic disorder (total=8)

A

Mirtazapine, lorazepam, clonazepam, diazepam, alprazolam, imipramine and clomipramine and reboxetine

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4
Q

Diagnostic criteria for panic disorder?

A

Both of the following:
-recurrent unexpected panic attacks
-more than one panic attack followed by more than one month of (1 or both):
Significant maladaptive change in behavior related to the attacks
Persistent concern about additional panic attacks or their consequence

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5
Q

Diagnosis criteria for panic attacks?

A

Abrupt surge of intense fear or intense discomfort that reaches a peak within minutes and include 4 or more of :

  • palpitations
  • heat wave or chills
  • sweating
  • nausea
  • dizziness, faint, ligt-headed
  • shaking
  • depersonalization or derealization
  • fear of dying or going crazy
  • shortness of breath
  • feeling of choking
  • chest pain or discomfort
  • paresthesia or numbness
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6
Q

DSM criteria for agoraphobia

A

Fear or anxiety about two or more of the following 5 group situations:

  • public transportation (bus, train, plane, ships)
  • open space (highway, market place, bridges, parking lots)
  • crowd or standing in line
  • being outside the home alone in other situations
  • being in cinema, theatres, shops

These situations are feared or avoided due to thoughts that escape might be difficult in the event of panic-like symptoms

These situations always provoke fear or anxiety and are actively avoided, endured with maked fear of anxiety or require the presence of a companion

The fear or anxiety is out of proportion to actual danger pose by the situation

Lasts more than 6 months and causes clinically significant distress or functional impairment

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7
Q

What is the treatment of specific phobias?

A

Exposure-based techniques, including virtual exposure, are highly effective, and are the foundation of treatment for specific phobias. Pharmacotherapy is generally unproven, and thus not recommended.

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8
Q

What are the dx criteria for SAD?

A

Marked fear or anxiety about social situation
-fear that actions or showing anxiety will result in negative evaluation (humiliation)
-social situation always provokes fear or anxiety and is actively avoided or endured with marked fear or anxiety
-the fear is out of proportion… for more than 6 mo…cause significant distress.
Specify is «performance only»

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9
Q

What are first-line pharmacological treatment for SAD? (Total=6)

A

Paxil, zolft, effexor xr, pregabaline, escitalopram, luvox

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10
Q

Name not recommended medications for SAD?

A

Buspirone, propranolol and atenolol (except for prn in performance situations), quetiapine, imipramine, levetiracetam

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11
Q

Name second line tx for SAD?

A

Citalopram, clonazepam, bromazepam, alprazolam, gabapentin and phenelzine

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12
Q

Name the DSM criteria for GAD?

A

Excessive worry about a number of events and activities (school, work)

  • individual finds it difficult to control the worry
  • this worry is associated with at least 3 of the following (restless, muscle tension, irritability, headache, easily fatigues, sleep disturbance, difficulty concentrating) for at least 6 months and causes significant distress…
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13
Q

What are the first line agents for GAD? (Total=7)

A

Escitalopram, venlafaxine xr, pregabaline, sertraline, paxil, duloxetine, agomelatine

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14
Q

Name second line tx for GAD?

A

Brupropion XL, quetiapine XR, vortioxetine, imipramine, buspirone, lorazepma, alprazolam, bromazepam, diazepam

Adjunctive therapy 2nd line: pregabaline
Adj thx 3rd line: abilify, olanzapine, risperidone and quetiapine

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15
Q

what is not recommended in GAD?

A

Ziprasidone as adjunct;

Beta-blockers, tiagabine

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16
Q

What is the most prevalent anxiety disorder?

A

Specific phobia, with social anxiety following closely (both around 10%)

17
Q

What is the age of onset of main anxiety disorders?

A

Social anxiety and specific phobia start the earliest, panic disorder early twenties, GAD bimodal (18 yo and 30-40 yo; mediam 31yo)

In elderly, specific phobia (fear of falls) and GAD are most common. Panic disorder prevalence decreases.

18
Q

What is the most frequent specific phobia?

A

Animals

19
Q

What is the most prevalent psychiatric disorder in children and adolescents?

A

Anxiety disorders

20
Q

Name DSM diagnostic criteria for separation anxiety?

A

Developmentally inappropriate and excessive anxiety concerning separation from home or from those to whom the individual is attaced, 3 or more of the following:
-recurrent excessive distress when separation from home or major attachment figures occurs or is anticipated
-persistent and excessive worry about losing, or about possible harm befalling, major attachment figures
-worry that untoward event will lead to separation from a major attachment figure (eg being kidnapped, getting lost)
-persistent reluctance to go to school or elsewhere because of fear of separation
-persistently and excessively fearful or reluctant to be alone or without a major attachment figure at home or without significant figures elsewhere
-persisten relunctance or refusal to go to sleep without begin near a major attachment figure or to sleep away from home
-repeated nightmares involving themes of separation
-repeated somatic complaints when separation from major attachment figue occurs or is anticipated
Lasting for at least 4 weeks (child-teen) or 6 months (adults)
Onset before 18 yo

21
Q

What is first line pharmaco for OCD?

A

SSRI: escitalopram, luvox, prozac, paxil and zoloft

22
Q

What is first line adj pharmacothx for OCD?

A

Abilify and risperidone

23
Q

What is second line pharmaco for OCD?

A

Clomipramine, mirtazapine, venlafaxine xr and citalopram

24
Q

What is not recommended as pharmaco in OCD?

A

Clonazepam, clonidine and desipramine

25
Q

Mean age of onset of OCD?

A

Twenties, but sx can occur below age 10, with few new cases after 30.

26
Q

Ratio homme femme ptsd?

A

2 femme pour 1 homme

27
Q

Risque de suicide avec ptsd?

A

Augment 2-3 fold

28
Q

Diagnostic criteria of PTSD?

A

Exposition to actual or threatened death, serious injury or sexual violation in the following ways:

  • directly experienced or witnessed
  • learned that trauma happened to close family member or friend
  • experience repeated exposure to aversive details of trauma

Cluster of sx:
>=1 of intrusion sx (intrusive distressive memories, nightmares, flashbacks)
>=1 of avoidance (memories or reminders)
>=2 negative alterations in mood or cognition (reduced interest, detachment, distorted blame, negative emotional state)
>=2 hyperarousal (irritable, agressive, reckless, hypervigilence, starteled, sleep, concentration)

More than one month

Specifier: With dissociative sx or delayed expression (fulll criteria not met 6mo after the event)

29
Q

What is a good strategy to prevent PTSD

A

Screening individuals after trauma ; those with sx will benefit from brief TF-CBT. Individual debrief not recommended (no evidence to comment on group debrief)

30
Q

What is not recommended in PTSD?

A

Early use of benzo after trauma increases the risk of PTSD. Lyrica and gabapentin have no effect on PTSD development

31
Q

what is first line pharmacothx in PTSD

A

Fluoxetine, paroxetine, venlafaxine xr and sertraline

32
Q

What is second line pharmaco in PTSD?

A

Mirtazapine, luvox and phenelzin

Adjunct eszopiclone, olanzzapine and risperidone

33
Q

What is not recommended in PTSD

A

Alprazolam, clonazepam, citalopram, desiramine, epival, olanzapine
As adjunct, bupropion, guanfacine, topamax, zolpidem

34
Q

What is recommended for ptsd-associated symptoms?

A

Nightmares: prazocin level 1
Flashbacks: naltrexone level 3
Trauma re-experiencing sx: fluphenazine level 3

35
Q

Other alternative therapies for ptsd?

A

RTMS was effective as monotherapy and as an adjunct to SSRI with ptsd (level 1)
Acupuncture (level 2)
Hypnotherapy and mantra (level 2)