Bacteriophage lambda replication Flashcards
Infection by temperate phages results in ?
prolonged,latent state of infection (lysogeny)
in a prophage where is carried the phage?
on the chromosome
prophage?
phage genome within the host cell chromosome
Lysogen?
bacterium that contains a prophage
how is it called when the propage exit the chromosome?
excision
what pathway emprunte the prophage after excision?
lytic pathway resulting in the production of new virus particles and host cell lysis
th phage Lamda’s genome how is it ?
linear dsDNA with cohesive ends
What are cohesive ends?
region of single-stranded complimentary DNA
when the cohesive ends join?
formes a circular molecule of dsDNA
the lamda genome is integrated at a specific site in the bacterial chromosome?
att λ site
the circular phage genome also has a?
att region
the att region is___ to the att λ site
homologous
what catalyzes the integration of the phage genome at this site ?
enzyme lamda integrase
where do we find the lamda integrase?
encoded on the phage genome
