Bacterial Structure 2&3. 6 Flashcards
Germination occurs with?
nutritional and environmental normality
Emergence of the vegetative cell is the result of?
endospore activation, germination, and subsequent outgrowth
how long does germination take?
90 minutes
Streptococcus mutans adhere to teeth better because they have a?
dextran and levan-polysaccharides CAPSULE/slime layer
Whats development is associated with caries tooth disease for Streptococcus mutans?
dextran and levan-polysaccharides CAPSULE/slime layer
glucosyl transferase
the enzyme which converts Sucrose (Glucose-O-Fructose) to glucose and fructose
Sucrose (Glucose-O-Fructose) is converted to?
- *a polymer of glucose [dextran (glucan)] with alpha-1-6/alpha-1-3 bonds
- *a polymer of fructose [levan (fructan) ] with beta 2-6/beta 1-2 bonds (fructosyltransferases)
what do you absolutely need in order to cause cavities?
glucosyl transferase enzyme
glucosyltransferases (GTF) are realeased by?
S. mutans and S. sanguis which cause caries
What are the 3 isoenzymes of GTF?
B, C, and D
GTF B catalyses the synthesis of?
an insoluble glucan from sucrose, composed mainly of alpha1,3-glucose moieties
GTF D synthesizes a water-soluble glucan of predominantly ___________ glucose
alpha1,6-linked glucose
What synthesizes both alpha1,3- and alpha1,6-linked glucans?
GTF C
Glucosyltransferases are good candidates for a human caries vaccine. Why?
It will inhibit the activity glucosyl transferase enzyme